子宫内膜异位囊肿患者输卵管系膜状态与卵巢囊肿剥除术后血清CA125、性激素水平的关系  

Relationship between mesosalpinx status and serum carbohydrate antigen 125 and sex hormone levels after ovarian cyst excision in patients with endometriotic cysts

作　　者：周玉敏 查正霞 方金枝 ZHOU Yumin;ZHA Zhengxia;FANG Jinzhi(Department of Gynaecology and Obstetrics,Anqing Shihua Hospital of Nanjing Drum Tower Hospital Group,Anqing 246000,Anhui,China)

机构地区：[1]南京鼓楼医院集团安庆石化医院妇产科,安徽安庆246000

出　　处：《中国性科学》2024年第2期122-125,共4页Chinese Journal of Human Sexuality

摘　　要：目的探究子宫内膜异位囊肿患者输卵管系膜状态与卵巢囊肿剥除术后血清糖类抗原125(CA125)、性激素水平的关系。方法纳入2020年1月至2022年12月就诊于南京鼓楼医院集团安庆石化医院的83例子宫内膜异位囊肿患者作为研究对象,均给予卵巢囊肿剥除术治疗。根据术前输卵管系膜与子宫内膜异位囊肿或附件粘连情况将其分为粘连组(n=32)和无粘连组(n=51),根据术中输卵管系膜有无活动性出血及血肿将其分为血管损伤组(n=37)和无血管损伤组(n=46)。分析患者输卵管系膜状态对术后血清CA125、性激素水平的影响。结果粘连组术后黄体生成素(LH)、雌二醇(E_(2))、卵泡刺激素(FSH)、抗米勒管激素(AMH)水平低于无粘连组(P<0.05);粘连组术后卵巢窦卵泡计数(AFC)少于无粘连组,卵巢体积小于无粘连组(P<0.05)。血管损伤组术后LH、E2、FSH及AMH水平低于无血管损伤组(P<0.05);血管损伤组术后卵巢AFC少于无血管损伤组,卵巢体积小于无血管损伤组(P<0.05)。结论子宫内膜异位囊肿患者输卵管系膜粘连及术中血管损伤可导致患者性激素水平降低,并影响其卵巢功能,但对血清CA125水平的影响不大。Objective To explore the relationship between mesosalpinx status and serum carbohydrate antigen 125(CA125)and sex hormone levels of after ovarian cyst excision in patients with endometriotic cyst.Methods A total of 83 patients with endometriotic cysts in Anqing Shihua Hospital of Nanjing Drum Tower Hospital Group from January 2020 to December 2022 were included as the research subjects.All patients were treated with ovarian cyst excision.According to the adhesion of preoperative mesosalpinx to the endometriotic cyst or the adnexa,the patients were divided into adhesion group(n=32)and non-adhesion group(n=51).The patients were classified into vascular injury group(n=37)and non-vascular injury group(n=46)according to whether there was active bleeding or hematoma in mesosalpinx during surgery.The effects of mesosalpinx status of patients on postoperative serum CA125 and sex hormone levels were analyzed.Results The levels of luteinizing hormone(LH),estradiol(E_(2)),follicle-stimulating hormone(FSH)and anti-Müllerian hormone(AMH)in adhesion group after surgery were lower than those in non-adhesion group(P<0.05).After surgery,the ovarian antral follicle count(AFC)in adhesion group was less than that in non-adhesion group,and the ovarian volume was smaller than that in non-adhesion group(P<0.05).The levels of LH,E2,FSH and AMH after surgery in vascular injury group were lower than those in non-vascular injury group(P<0.05).The ovarian AFC after surgery in vascular injury group was less than that in non-vascular injury group,and the ovarian volume was smaller compared with that in non-vascular injury group(P<0.05).Conclusions Mesosalpinx adhesion and intraoperative vascular injury in patients with endometriotic cysts can lead to the sex hormone levels reduction and affect the ovarian function,but they have little effect on serum CA125 level.

关 键 词：子宫内膜异位囊肿 输卵管系膜状态 卵巢囊肿剥除术 糖类抗原125 性激素 

分 类 号：R711[医药卫生—妇产科学]