成人普通变异型免疫缺陷病1例报道并文献复习  

Adult common variable immunodeficiency: a case report and literature review

作　　者：钟海媚 凌华湘 黄立霞 王红燕 ZHONG Haimei;LING Huaxiang;HUANG Lixia;WANG Hongyan(Department of General Practice,Union Shenzhen Hospital of Huazhong University of Science and Technology,Shenzhen,Guangdong 518052,China;不详)

机构地区：[1]华中科技大学协和深圳医院全科医学科,广东深圳518052 [2]暨南大学第二临床医学院,广东深圳518020 [3]华中科技大学协和深圳医院呼吸与危重症医学科 [4]华中科技大学协和深圳医院感染科

出　　处：《中华全科医学》2024年第1期172-174,共3页Chinese Journal of General Practice

基　　金：广东省医学科学技术研究基金项目(A2022497)。

摘　　要：本文报道1例成人普通变异型免疫缺陷病(CVID),患者男性,38岁,发病前身体素质良好,10年前开始因反复发生肺部及其他部位感染多次住院,此次因“肺部感染”再次入院,入院查免疫球蛋白普遍低下,排除其他引起免疫球蛋白低下的可能原因后考虑诊断CVID,予积极静脉补充免疫球蛋白、抗感染等治疗后症状缓解,但予静脉输入丙种球蛋白后复查免疫球蛋白并无明显提高,建议患者出院后长期规律补充丙种球蛋白后复查。This paper reports a case of adult common variable immunodeficiency(CVID).The patient was a 38-year old man who had been in good health prior to the onset of the disease and had been hospitalized several times over the previous 10 years for pulmonary and other infections.This time,the patient was hospitalized again for a lung infection and was found to have low immunoglobulin levels.After excluding other possible causes of low immunoglobulin,the patient was diagnosed with CVID.The symptoms improved after intravenous immunoglobulin,anti-infective and other treatments.However,there was no significant improvement in immunoglobulin.It is suggested that the patient should be regularly supplemented with intravenous immunoglobulin for a long time after discharge.The relevant literature was also reviewed in this paper.

关 键 词：普通可变性免疫缺陷 疾病特征 免疫 

分 类 号：R593.3[医药卫生—内科学]