骨疏康胶囊临床综合评价  

Clinical Comprehensive Evaluation on Gushukang Capsules

作　　者：王炎[1] 何婷[2] 郭媛媛 李佳怡 顾媛媛[2] 曹俊岭[3] WANG Yan;HE Ting;GUO Yuanyuan;LI Jiayi;GU Yuanyuan;CAO Junling(School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 100105,China;Dept.of Pharmacy,Dongfang Hospital of Beijing University of Chinese Medicine,Beijing 100078,China;Luoyang Branch Hospital,Dongzhimen Hospital of Beijing University of Chinese Medicine,Henan Luoyang 471000,China)

机构地区：[1]北京中医药大学中药学院,北京100105 [2]北京中医药大学东方医院药学部,北京100078 [3]北京中医药大学东直门医院洛阳医院,河南洛阳471000

出　　处：《中国医院用药评价与分析》2024年第2期227-231,共5页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：北京市中医管理局-中药临床应用评价项目(2022年)。

摘　　要：目的:针对骨疏康胶囊进行综合评价,以期为骨疏康胶囊的临床合理应用提供参考。方法:应用循证医学、流行病学、医学统计学等知识体系,结合相关文献、资料和药品生产企业提供的信息,对骨疏康胶囊的有效性、安全性、经济性、药学特性、质量等方面进行综合评价研究。结果:骨疏康胶囊有效性的Meta分析结果显示,其临床效果优于单一钙剂,可以有效地针对原发性骨质疏松症,且不良反应发生率低;药物吸收快,生物利用度高,服用方便。药品质量符合国家标准且可控,药品说明书及标签、包装符合现行规定。药品价格合理且已被纳入国家医保目录,具有一定的经济性。结论:骨疏康胶囊安全性高,质量可控,临床疗效显著,服用方便,经济性尚可。但部分研究证据级别相对较低,其体内药学特性和可及性方面的研究相对较少,建议进一步深入探讨。OBJECTIVE:To perform comprehensive evaluation on Gushukang capsules,so as to provide reference for the clinical rational application of Gushukang capsules.METHODS:Knowledge system of evidence-based medicine,epidemiology and medical statistics was used,in combination with the relevant literature,data and information provided by drug manufacturers,to conducted a comprehensive evaluation study on efficacy,safety,economical efficiency,pharmacological characteristics and quality of Gushukang capsules.RESULTS:Meta-analysis on efficacy of Gushukang capsules showed that its clinical effect was better than single calcium agent,which can effectively target primary osteoporosis with a low incidence of adverse drug reactions;with quick absorption,high bioavailability and convenient administration.And the quality of the drug met the national standard and was controllable,its dispensatory,labeling and packaging complied with the current regulations.The price of the drug was reasonable and had been included in the national reimbursement drug list,with a certain degree of economical efficiency.CONCLUSIONS:Gushukang capsules have high safety,controllable quality,significant clinical efficacy,convenient administration and reasonable economical efficiency.However,the evidence level of part of studies is relatively low,and relatively few studies have been conducted on its in vivo pharmacological properties and accessibility,and further in-depth exploration is recommended.

关 键 词：骨疏康胶囊 中成药 综合评价 

分 类 号：R932[医药卫生—生药学]