无痛胃肠镜检查中应用瑞马唑仑的麻醉效果分析  

Analysis of anaesthesia effect of remimazolam in painless gastroscope

作　　者：王梅静[1] WANG Mei-jing(Jinan Third People's Hospital Jinan,Jinan 250100,China)

机构地区：[1]济南市第三人民医院,250100

出　　处：《中国实用医药》2024年第4期19-22,共4页China Practical Medicine

摘　　要：目的分析瑞马唑仑应用到无痛胃肠镜检查中的麻醉效果。方法82例接受无痛胃肠镜检查患者,根据计算机抽签法分成参照组和研讨组,每组41例。参照组接受丙泊酚进行麻醉诱导,研讨组接受瑞马唑仑进行麻醉诱导。对比两组患者的麻醉优良率、麻醉情况、血流动力学指标[平均动脉压(MAP)、呼吸频率(RR)、心率(HR)]及不良反应发生率。结果研讨组患者的麻醉优良率95.12%高于参照组的80.49%(P<0.05)。研讨组认知功能评分(27.62±0.54)分高于参照组的(24.32±1.41)分,麻醉诱导时间(33.45±4.17)s、苏醒时间(4.95±1.13)min、定向力恢复时间(8.62±1.37)min均短于参照组的(41.72±4.69)s、(6.24±1.35)min、(10.47±1.02)min(P<0.05)。给药后,研讨组的MAP(65.52±6.35)mm Hg(1 mm Hg=0.133 kPa)、RR(16.08±1.51)次/min、HR(65.87±3.04)次/min均高于参照组的(61.47±6.03)mm Hg、(14.82±1.16)次/min、(63.14±3.02)次/min(P<0.05)。研讨组患者的不良反应发生率9.76%明显低于参照组的31.71%(P<0.05)。结论无痛胃肠镜检查麻醉患者应用瑞马唑仑能取得良好的麻醉效果,对患者血流动力学的影响较小,能缩短麻醉诱导及患者恢复时间,降低不良反应发生率,有较高的参考价值。Objective To analyze the anaesthesia effect of remimazolam in painless gastroscope.Methods 82 patients who received painless gastroscopy were divided into a reference group and a study group based on the computer lottery method,with 41 cases in each group.The reference group received propofol for anesthesia induction,and the study group received remimazolam for anesthesia induction.The excellent and good rate of anesthesia,anesthesia situation,hemodynamic indicators[mean arterial pressure(MAP),respiratory rate(RR),heart rate(HR)],and adverse reaction rate of the two groups were compared.Results The excellent and good rate of anesthesia was 95.12%in the study group,which was significantly higher than 80.49%in the reference group(P<0.05).The cognitive function score of(27.62±0.54)points in the study group was higher than(24.32±1.41)points in the reference group;in the study group,the anesthesia induction time was(33.45±4.17)s,the recovery time was(4.95±1.13)min and the orientation recovery time was(8.62±1.37)min,which were all shorter than(41.72±4.69)s,(6.24±1.35)min and(10.47±1.02)min in the reference group(P<0.05).After administration,the study group had MAP of(65.52±6.35)mm Hg(1 mm Hg=0.133 kPa),RR of(16.08±1.51)times/min,HR of(65.87±3.04)beats/min,which were higher than(61.47±6.03)mm Hg,(14.82±1.16)times/min and(63.14±3.02)beats/min in the reference group(P<0.05).The incidence of adverse reactions was 9.76%in the study group,which was significantly lower than 31.71%in the reference group(P<0.05).Conclusion Remimazolam can achieve good anesthetic effect in patients undergoing painless gastroscopy with little influence on hemodynamics,shorten the induction of anesthesia and recovery time of patients,and reduce the incidence of adverse reactions,which has high reference value.

关 键 词：瑞马唑仑 无痛胃肠镜检查 麻醉 血流动力学 

分 类 号：R614[医药卫生—麻醉学]