胎儿生长受限宫内脑损伤相关机制研究进展  

Recent research advancements in mechanisms underlying intrauterine brain injury in fetuses with fetal growth restriction

作　　者：张有振 黄娜娜 赵扬玉[1] Zhang Youzhen;Huang Nana;Zhao Yangyu(Department of Obstetrics and Gynecology,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院妇产科,北京100191

出　　处：《中华围产医学杂志》2024年第2期161-165,共5页Chinese Journal of Perinatal Medicine

基　　金：国家自然科学基金(81971399)。

摘　　要：胎儿生长受限(fetal growth restriction,FGR)脑损伤的发病机制可能与氧化应激及神经炎症有关,但确切机制尚不清楚。本文主要围绕FGR脑损伤相关的解剖学改变、潜在的病理生理过程以及不同脑细胞类群参与FGR的具体分子机制进行综述。The pathogenesis of brain injury in fetal growth restriction(FGR)fetuses is likely associated with oxidative stress and neuroinflammation,although the exact mechanisms are not fully understood.This article mainly reviews the anatomical alterations,potential pathophysiological processes,and the specific molecular mechanisms involving various types of brain cells in FGR.

关 键 词：胎儿生长迟缓 神经发育障碍 少突神经胶质 神经元 

分 类 号：R714.5[医药卫生—妇产科学]