吴门医派络病理论干预治疗PCI术后气虚血瘀证的临床治疗效果  

Observation on the Therapeutic Effect of Wumen Medical School's Theory of Collateral Disease Intervention on Qi Deficiency and Blood Stasis Syndrome After PCI Surgery

作　　者：张文英[1] 李铭来 ZHANG Wenying;LI Minglai(Department of Cardiology,Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou Jiangsu 215009,China)

机构地区：[1]南京中医药大学附属苏州市中医医院心内科,江苏苏州215009

出　　处：《中国卫生标准管理》2024年第3期132-135,共4页China Health Standard Management

摘　　要：目的观察吴门医派络病理论干预治疗PCI术后气虚血瘀证的疗效。方法采用随机对照研究方法,共纳入南京中医药大学附属苏州市中医医院2018年1月—2022年1月就诊的PCI术后气虚血瘀证患者70例,实际纳入对照组30例,治疗组32例,脱落8例,脱落率为11.43%。对照组给予西医常规治疗,治疗组给予加味生脉散配伍活血化瘀药干预治疗结合西医常规治疗。观察治疗前和治疗3个月后中医证候改善率、生活质量评估情况、超敏C反应蛋白、血清N末端B型利钠肽原(N-terminal pro-B-type natriuretic peptide,NT-proBNP)水平的变化差异情况。结果治疗3个月后,治疗组中医症候改善率为84.38%,对照组为53.33%,治疗组高于对照组(P<0.05)。治疗3个月后,治疗组的活动受限程度、心绞痛发作频率、心绞痛稳定状态、疾病认识程度、治疗满意程度等均优于对照组,差异有统计学意义(P<0.05)。治疗后30 d治疗组hs-CRP[(5.17±4.13)ng/L]及NT-proBNP[(860.70±329.60)pg/mL]均低于对照组[(13.60±5.65)ng/L,(1402.40±401.66)pg/mL],差异有统计学意义(P<0.05)。结论吴门医派络病理论指导下加味生脉散配伍活血化瘀结合西医常规治疗,能更有效改善PCI术后气虚血虚证患者的生活质量,降低术后心血管不良事件发生。Objective To observe the therapeutic effect of Wumen Medical School's theory of collateral disease intervention on Qi deficiency and blood stasis syndrome after PCI surgery.Methods Using a randomized controlled study method,a total of 70 patients with Qi deficiency and blood stasis syndrome after PCI who visited Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine from January 2018 to January 2022 were included.In fact,30 patients were included in the control group,32 patients in the treatment group,and 8 patients were excluded,with an dropout rate of 11.43%.The control group received routine Western medicine treatment.The treatment group was treated with modified Shengmai Powder combined with blood activating and stasis resolving drugs for intervention therapy,combined with routine Western medicine treatment,the differences in changes in traditional Chinese medicine syndrome scores and improvement rates,quality of life assessment,hypersensitive C-reactive protein,and serum N-terminal pro-B type natriuretic peptide(NT-proBNP)levels before and after 3 months of treatment were observed.Results After 3 months of treatment,the improvement rate of traditional Chinese medicine symptoms in the treatment group was 84.38%,while in the control group it was 53.33%.The treatment group was higher than the control group(P<0.05).After 3 months of treatment,the treatment group was superior to the control group in terms of limited mobility,frequency of angina attacks,stable angina status,disease awareness,and treatment satisfaction,with statistical significance(P<0.05).After 30 d of treatment,the hs-CRP[(5.17±4.13)ng/L]and NT-proBNP[(860.70±329.60)pg/mL]in the treatment group were lower than those in the control group[(13.60±5.65)ng/L,(1402.40±401.66)pg/mL],and the differences were statistically significant(P<0.05).Conclusion Under the guidance of Wumen Medical School's theory of collateral disease,the combination of modified Shengmai San and Huoxue Huayu combined with conventional Western medicine treatme

关 键 词：吴门医派络病理论 经皮冠状动脉介入术后 气虚血瘀 中西医结合 加味生脉散 疗效 

分 类 号：R542[医药卫生—心血管疾病]