生物样品的预处理技术研究进展  

Advance in Pretreatment Techniques for Biological Samples

作　　者：尤斯涵 殷宏艳 杨宋蕊 刘鑫淼 郭春燕[1] YOU Si-han;YIN Hong-yan;YANG Song-rui;LIU Xin-miao;GUO Chun-yan(Department of Pharmacy,Hebei North University,Hebei Key Laboratory of Neuropharmacology,Zhangjiakou,075000,China)

机构地区：[1]河北北方学院药学院,河北省神经药理学重点实验室,张家口075000

出　　处：《神经药理学报》2023年第5期52-59,共8页Acta Neuropharmacologica

摘　　要：基于生物样品具有药物种类繁多、理化性质各异、生物介质组分复杂的特点,生物样品的预处理产生了多种技术和方法。基于以上背景,该文综述了近年来在体内药物分子中生物样品的预处理方法,以期为不同生物样品的预处理提供参考。Due to the diverse types of drugs,diverse physicochemical properties,and complex composition of biological media in biological samples,various technologies and methods have emerged for the pre-treatment of biological samples.Based on the above background,this article reviews the pre-treatment methods of biological samples in vivo drug molecules in recent years,with the aim of providing reference for the pre-treatment of different biological samples.

关 键 词：生物样品 预处理 体内药物分析 

分 类 号：R963[医药卫生—微生物与生化药学]