基于决策树模型的冰黄肤乐软膏治疗湿疹的药物经济学评价  

Pharmacoeconomic Evaluation of the Ointment Treatment for Eczema based on Decision Tree Model

作　　者：王馥丽 崔鑫 谢雁鸣[1] WANG Fu-Li;CUI Xin;XIE Yan-Ming*(Institute of Clinical Basic Medicine of Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700

出　　处：《中国药物经济学》2023年第12期17-20,共4页China Journal of Pharmaceutical Economics

基　　金：2021年岐黄学者支持项目(国中医药人教函[2022]6号)。

摘　　要：目的 评估冰黄肤乐软膏治疗湿疹的经济性。方法 根据本研究的随机对照试验(RCT)结果,以卫生体系角度为出发点,采用决策树模型对治疗湿疹所用的冰黄肤乐软膏和复方醋酸地塞米松软膏的经济性进行评估。结果 相比复方醋酸地塞米松软膏,使用冰黄肤乐软膏治疗湿疹时,患者每多提升17.8%的效果,需要多花费114.65元,当患者个人意愿支付价格高于114.65元时,冰黄肤乐软膏组更具有经济性的概率优于复方醋酸地塞米松软膏组,敏感性分析结果表明了基础分析结果较稳定。冰黄肤乐软膏组的临床疗效、药品单价和患者用药依从性对研究结果有一定影响,具有更高经济性概率的干预方案同基础分析结果一致。结论 采用冰黄肤乐软膏治疗湿疹比复方醋酸地塞米松软膏更具经济性。Objective To evaluate the economics of Binghuang ointment for treating eczema.Methods Based on the results of a randomized controlled trial conducted in this study,a decision tree model was used to evaluate the economic efficiency of the use of Huanfule ointment and compound betamethasone dipropionate ointment for the treatment of eczema from the perspective of the healthcare system.The results showed that compared to compound betamethasone dipropionate ointment,Huanfule ointment can significantly reduce the number of eczema outbreaks before and after treatment,and is also more cost-effective in terms of drug costs and annual outpatient diagnosis and treatment expenses.The robustness of the results was ensured through sensitivity analysis.Results The results of the cost-effect analysis show that the cost of the ointment group is higher than that of the control group,and the effect obtained is also higher than that of the control group.The incremental cost-effect ratio is 17.8%,which is about 1%of the per capita disposable income in China in 2021.The sensitivity analysis results show that the results of this study are relatively stable.Conclusion The cost of the Huanfule ointment group was higher than that of the control group,while the results obtained were also higher than those of the control group,with an incremental cost-effectiveness ratio of 17.8%.Sensitivity analysis results showed that the results were stable.Conclusion The use of Huanfule ointment for the treatment of eczema is more cost-effective than the use of compound betamethasone dipropionate ointment.

关 键 词：冰黄肤乐软膏 湿疹 药物经济学评价 决策树模型 复方醋酸地塞米松软膏 

分 类 号：R758.23[医药卫生—皮肤病学与性病学] R956[医药卫生—临床医学]