小儿氨基酸的早期合理应用在新生儿肠外营养中的疗效分析  

Analysis of the therapeutic effect of early and rational application of amino acids in neonatal parenteral nutrition

作　　者：刘向荣[1] 祝睿颖 Liu Xiangrong;Zhu Ruiying(People's Hospital of Hejian City,Cangzhou,Hebei 062450,China;Chengde Medical Col lege,Chengde,Hebei 067000,China)

机构地区：[1]河北省河间市人民医院,河北沧州062450 [2]承德医学院,河北承德067000

出　　处：《首都食品与医药》2024年第4期65-67,共3页Capital Food Medicine

摘　　要：目的 观察小儿氨基酸的早期合理应用在新生儿肠外营养支持治疗中的应用效果.方法 纳入河间市人民医院收治的200例新生儿患者为研究观察主体,采集时间2021年1月10日-2022年12月30日.将患者依据随机抽签法分为两组,对照组[100例新生儿肠外营养支持治疗,其氨基酸初始剂量为低剂量,按0.5g/(kg·d),出生24小时后开始应用]和实验组[100例新生儿肠外营养支持治疗,其氨基酸初始剂量为高剂量,按1.5-2.0g/(kg·d),出生24小时之内开始应用].两组除小儿氨基酸外,其他肠外营养药物的成分及使用方法一致.观察两组患儿营养情况、并发症发生率、体格生长情况.结果 ①营养情况:治疗前,两组患儿血清总蛋白、铁蛋白、血红蛋白水平比较,差异无统计学意义(P>0.05);治疗后,实验组血清总蛋白、铁蛋白、血红蛋白水平高于对照组,差异有统计学意义(P<0.05).②并发症发生率:治疗后实验组并发症发生率低于对照组,差异有统计学意义(P<0.05).③体格生长情况:治疗前,两组患儿体重、身长、头围比较,差异无统计学意义(P>0.05);治疗后,实验组体重、身长、头围大于对照组,差异有统计学意义(P<0.05).结论 新生儿肠外营养支持治疗方案中,小儿氨基酸注射液的早期合理应用可以促进新生儿营养状态改善,预防新生儿并发症,加速患儿康复,可推广应用.Objective Observes the application effect of early and reasonable application of amino acids in neonatal parenteral nutrition support treatment.Methods 200 newborn patients admitted to our hospital were included as the research observation subjects,and the collection time was January 10,2021 to December 30,2022.The patients were randomly divided into two groups based on the method of drawing lots:the control group[100 newborn patients received parenteral nutrition support treatment with an initial amino acid dose of 0.5g/(kg:d)at a low dose and starting 24 hours after birth]and the experimental group[100 newborn patients received parenteral nutrition support treatment with an initial amino acid dose of 1.5-2.0g/(kg d)at a high dose and starting within 24 hours of birth].The composition and usage of parenteral nutrition drugs in both groups were consistent,except for pediatric amino acids.The nutritional status,incidence of complications,physical growth of two groups were observed.Results ①Nutritional status:before treatment,there was no statistically significant difference in serum total protein,ferritin,and hemoglobin levels between the two groups of newborn patients(P>0.05).after treatment,the serum levels of total protein,ferritin,and hemoglobin in the experimental group were higher than those in the control group,with statistical significance(P<0.05).②The incidence of complications:after treatment,the incidence of complications in the experimental group was lower than that in the control group,with a statistically significant difference(P<0.05).③Physical growth:before treatment,there was no statistically significant difference in weight,length,and head circumference between the two groups of children(P>0.05).After treatment,the weight,length,and head circumference of the experimental group were significantly bigger than those of the control group(P<0.05).Conclusions The early and reasonable application of pediatric amino acid injection in the treatment plan of parenteral nutrition support for newborns c

关 键 词：新生儿 肠外营养支持治疗 氨基酸注射液 铁蛋白 血清总蛋白 

分 类 号：R723.13[医药卫生—儿科]