肝移植术后胆道吻合口狭窄的诊疗进展  

Progress in diagnosis and treatment of biliary anastomotic stricture after liver transplantation

作　　者：冯彦杰 李敬东[2] 李强[1] 龚财芳 陶计林 Feng Yanjie;Li Jingdong;Li Qiang;Gong Caifang;Tao Jilin(Department of Hepatobiliary Surgery,the Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院肝胆外科,四川南充637000 [2]川北医学院肝胆胰肠疾病研究所

出　　处：《器官移植》2024年第2期297-302,共6页Organ Transplantation

基　　金：国家卫生健康委医药卫生科技发展研究项目(WA2021RW26);川北医学院附属医院科研发展计划项目(2021YS004)。

摘　　要：近年来,随着器官保存、手术技术、围手术期管理及免疫抑制方案的发展,肝移植手术成功率和受者生存率明显提高,已成为终末期肝病患者的最佳治疗方案。但胆道并发症依然是肝移植术后常见的并发症,尤其是胆道吻合口狭窄,严重的胆道吻合口狭窄不仅会增加治疗成本,还会导致移植物丢失,甚至影响受者生存率。因此,胆道吻合口狭窄的及时诊断和治疗对于提高肝移植术后受者生存率至关重要。本文就肝移植术后胆道吻合口狭窄的危险因素、临床症状、诊断及治疗进行综述,以期为肝移植术后胆道吻合口狭窄的研究和诊疗提供新的思路,进一步提高肝移植手术效果和受者生存质量。In recent years,with the development of organ preservation,surgical techniques,perioperative management and immunosuppression regimens,the success rate of liver transplantation and survival rate of the recipients have been significantly enhanced.Liver transplantation has become the optimal treatment for patients with end-stage liver disease.However,biliary complications still commonly occur after liver transplantation,especially biliary anastomotic stricture.Severe biliary anastomotic stricture will not only increase the cost of treatment,but also lead to graft loss and even affect the survival rate of recipients.Therefore,timely diagnosis and treatment of biliary anastomotic stricture play a significant role in improving the survival rate of liver transplant recipients.In this article,the risk factors,clinical symptoms,diagnosis and treatment of biliary anastomotic stricture after liver transplantation were reviewed,aiming to provide novel ideas for the research,diagnosis and treatment of biliary anastomotic stricture after liver transplantation,and further enhance clinical efficacy of liver transplantation and the quality of life of recipients.

关 键 词：肝移植 胆道并发症 胆道吻合口狭窄 胆漏 内镜逆行胰胆管造影 经皮肝胆管造影术 支架植入 磁压榨吻合 

分 类 号：R617[医药卫生—外科学] R575[医药卫生—临床医学]