艾司洛尔和利多卡因对气管插管血流动力学的影响比较  

Comparison of the Effects of Esmolol and Lidocaine on Tracheal Intubation Hemodynamics

作　　者：陈烨[1] 邹聪华[1] 吴晓丹[1] CHEN Ye;ZOU Conghua;WU Xiaodan(Department of Anesthesiology,South Hospital of Fujian Provincial Hospital,Fuzhou,Fujian Province,350000 China)

机构地区：[1]福建省立医院南院麻醉科,福建福州350000

出　　处：《中外医疗》2023年第36期82-84,117,共4页China & Foreign Medical Treatment

摘　　要：目的 对比分析β受体阻滞剂艾司洛尔与利多卡因对气管插管后血流动力学的影响。方法 随机选择2020年10月—2022年2月于福建省立医院南院行甲状腺手术的69例患者作为研究对象,在全身麻醉下进行气管插管。按随机数表法分为两组,接受艾司洛尔推注后泵入,即艾司洛尔组34例,接受利多卡因推注后泵入,即利多卡因组35例。对比两组心率、血压及咳嗽或体动的发生率。结果 艾司洛尔组插管后心动过速发生率为5.9%,低于利多卡因组28.5%,差异有统计学意义(χ^(2)=13.235,P<0.05)。气管插管后,艾司洛尔组的平均心率低于利多卡因,差异有统计学意义(P<0.05)。结论 与利多卡因相比,艾司洛尔是一种安全且更有效的干预措施,可降低心动过速的发生率并在气管插管后立即控制心率。Objective To compare the effects of β-receptor blocker esmolol and lidocaine on hemodynamics after tracheal intubation.Methods A total of 69 patients who underwent thyroid surgery in the South Hospital of Fujian Provincial Hospital from October 2020 to February 2022 were randomly selected as the study subjects,and endotracheal intubation was performed under general anesthesia.The patients were randomly divided into two groups by random number table method,injected with esmolol(34 cases) or lidocaine(35 cases).Heart rate,blood pressure and incidence of cough or body movement were compared between the two groups.Results The incidence of tachycardia after intubation was 5.9% in Esmolol group,which was lower than 28.5% in lidocaine group,and the difference was statistically significant(χ^(2)=13.235,P<0.05).After endotracheal intubation,the mean heart rate of esmolol group was lower than that in the lidocaine group,and the difference was statistically significant(P<0.05).Conclusion Compared with lidocaine,esmolol is a safe and more effective intervention to reduce the incidence of tachycardia and control heart rate immediately after tracheal intubation.

关 键 词：艾司洛尔 气管插管 全身麻醉 利多卡因 心动过速 

分 类 号：R5[医药卫生—内科学]