微量泵持续泵入胰岛素治疗重症糖尿病酮症酸中毒患者的疗效及对血糖水平、胰岛素用量的影响  

Effect of Continuous Pumping of Insulin by Micropump in the Treatment of Patients with Severe Diabetic Ketoacidosis and the Influence of Insulin Dosage on Blood Glucose Level

作　　者：李伟 蒋兴 吴建光 LI Wei;JIANG Xing;WU Jianguang(Department of Critical Care Medicine,Shaowu Municipal Hospital,Shaowu,Fujian Province,354000 China)

机构地区：[1]福建省邵武市立医院重症医学科,福建邵武354000

出　　处：《糖尿病新世界》2023年第24期167-170,共4页Diabetes New World Magazine

摘　　要：目的研究微量泵持续泵入胰岛素治疗重症糖尿病酮症酸中毒患者的实际应用效果。方法选取2021年1月—2023年4月期间于福建省邵武市立医院进行治疗的84例重症糖尿病酮症酸中毒患者作为研究对象,根据住院编号的奇偶数分为对照组42例(奇数)和观察组42例(偶数)。对照组接受静脉滴注胰岛素治疗,观察组接受微量泵持续泵入胰岛素治疗。比较两组临床疗效、血糖水平、胰岛素用量及发生低血糖次数。结果治疗后,观察组临床疗效优于对照组,差异有统计学意义(P均<0.05)。观察组血糖水平均低于对照组,差异有统计学意义(P均<0.05)。观察组胰岛素用量、低血糖发生次数均少于对照组,差异有统计学意义(P均<0.05)。结论胰岛素微量泵持续泵入方式在治疗重症糖尿病酮症酸中毒患者方面,展现出较快地控制血糖水平、迅速稳定血液中血酮和尿酮体浓度、减少胰岛素用量及低血糖的发生次数等优点,临床疗效较高。Objective To study the effect of micropump continuous pumping insulin in the treatment of patients with severe diabetic ketoacidosis.Methods A total of 84 patients with severe diabetic ketoacidosis who were treated in Sha-owu Municipal Hospital of Fujian Province from January 2021 to April 2023 were selected as the study objects,and were divided into control group(42 cases)(odd number)and observation group(42 cases)(even number)according to the odd and even number of hospitalization numbers.The control group received intravenous insulin therapy,and the observation group received continuous insulin therapy with micropump.The clinical efficacy,blood glucose level,insu-lin dosage and frequency of hypoglycemia were compared between the two groups.Results After treatment,the clini-cal efficacy of the observation group was better than that of the control group,and the difference was statistically sig-nificant(all P<0.05).The blood glucose level of observation group was lower than that of control group,and the differ-ence was statistically significant(all P<0.05).The dosage of insulin and the frequency of hypoglycemia in the observa-tion group were lower than those in the control group,and the differences were statistically significant(both P<0.05).Conclusion In the treatment of patients with severe diabetic ketoacidosis,insulin micropump continuous pumping has shown the advantages of rapidly controlling blood glucose level,rapidly stabilizing the concentration of blood ketone and urine ketone bodies,reducing the dosage of insulin and the frequency of hypoglycemia,and has high clinical efficacy.

关 键 词：微量泵 胰岛素 血糖水平 重症糖尿病酮症酸中毒 

分 类 号：R587[医药卫生—内分泌]