口腔医院种植患者术前血清感染性指标检测情况  

Serum infectious indicators of patients before dental implant surgery in a stomatological hospital

作　　者：蒋莉莉 陈鹏 张晓荣 徐新阳 孟秋禹 祁冬 宋有文 王东雪 JIANG Lili;CHEN Peng;ZHANG Xiaorong;XU Xinyang;MENG Qiuyu;QI Dong;SONG Youwen;WANG Dongxue(Department of Healthcare-associated Infection Management,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University,Jinan 250012,Shandong,China;Shandong Hongrun Compressor Technology Company Limited,Zibo 255000,Shandong,China;Medical Department,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University,Jinan 250012,Shandong,China;Clinical Laboratory,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University,Jinan 250012,Shandong,China)

机构地区：[1]山东大学齐鲁医学院口腔医学院·口腔医院医院感染管理部,山东济南250012 [2]山东宏润空压机科技有限公司,山东淄博255000 [3]山东大学齐鲁医学院口腔医学院·口腔医院医务部,山东济南250012 [4]山东大学齐鲁医学院口腔医学院·口腔医院检验科,山东济南250012

出　　处：《山东大学学报（医学版）》2024年第1期15-20,共6页Journal of Shandong University:Health Sciences

基　　金：山东省科技型中小企业创新能力提升工程(2022TSGC2268);山东省卫生健康委员会医疗质量管理工作项目(2020-11)。

摘　　要：目的通过对某口腔医院种植患者术前乙型肝炎表面抗原(hepatitis B surface antigen,HBsAg)、丙型肝炎抗体(hepatitis C virus antibody,Anti-HCV)、梅毒螺旋体抗体(treponema pallidum antibody,Anti-TP)和人类免疫缺陷病毒抗体(human immunodeficiency virus antibody,Anti-HIV)4项血清感染性指标检出状况进行回顾性分析,了解种植患者血清感染性指标的流行情况。方法对2017年1月至2022年12月在某口腔医院施行口腔种植术,并在该院完成术前血清感染性指标检测的5896例患者资料进行回顾性分析,比较检测结果在性别、年龄等一般资料上的差异。结果5896例口腔种植患者术前4项血清感染性指标阳性指标数共计197例,总体阳性检出率为3.34%(197/5896)。其中,HBsAg、Anti-HCV和Anti-TP的阳性检出率分别为2.75%(162/5896)、0.24%(14/5896)和0.36%(21/5896),未检出Anti-HIV阳性感染者。HBsAg、Anti-HCV与Anti-TP阳性检出率之间的差异具有统计学意义(χ2=214.747,P<0.001);不同年龄组HBsAg阳性检出率之间的差异具有统计学意义(χ2=8.074,P=0.018)。结论口腔医院种植患者术前血清感染性指标存在一定阳性检出率。建议口腔专业医务人员在口腔诊疗过程中严格执行预检分诊,加强医院感染防控措施落实,加大对口腔门诊患者血清感染性指标的筛检力度,同时卫生健康管理部门加强对疫苗接种等传染病防控知识的宣传教育,以降低血源性病原体交叉感染风险。Objective To explore the prevalence of serum infectious indicators of implant patients,including hepatitis B surface antigen(HBsAg),hepatitis C virus antibody(Anti-HCV),treponema pallidum antibody(Anti-TP)and human immunodeficiency virus antibody(Anti-HIV).Methods A retrospective analysis was conducted on the data of 5,896 patients who underwent dental implantion surgery and completed preoperative serum infectivity test in a stomato logical hospital during Jan.2017 and Dec.2022,and the differences in general data such as gender and age were compared.Results Among the 4 serum infectious indicators in 5,896 patients,197 were positive,with an overall positive detection rate of 3.34%(197/5896).The positive detection rate of HBsAg,Anti-HCV and Anti-TP were 2.75%(162/5896),0.24%(14/5896)and 0.36%(21/5896),respectively(χ2=214.747,P<0.001).No Anti-HIV positive individual was identified.The differences in HBsAg positive detection rate among different age groups were statistically significant(χ2=8.074,P=0.018).Conclusion There is a certain positive detection rate of preoperative serum infectious indicators in dental implant patients.It's recommended that dental personnel strictly implement pre-examination and triage,strengthen the implementation of hospital infection prevention and control measures,increase the screening of serum infectious indicators.Meanwhile,the health managernent department should strengthen publicity and education on the knowledge of infectious diseases such as vaccination to reduce the risk of cross infection of blood borne pathogens.

关 键 词：口腔种植术 血清感染性指标 血源性病原体 医院感染 阳性检出率 

分 类 号：R183.7[医药卫生—流行病学]