新生儿肠沙门菌肠道亚种沃兴顿株引起血流感染1例  

A case of neonatal bloodstream infection caused by Salmonella enterica subsp.enterica Serovar Worthington Strain

作　　者：屈龙凤 张亚运 Qu Longfeng;Zhang Yayun(Medicine Laboratory of Chongqing University JiangJin Hospital,Chongqing 402260,China;Medicine Laboratory of Chongqing JiangJin District Hospital of Chinese Medicine,Chongqing 402260,China)

机构地区：[1]重庆大学附属江津医院检验科,重庆402260 [2]重庆市江津区中医院检验科,重庆402260

出　　处：《中华检验医学杂志》2024年第2期184-186,共3页Chinese Journal of Laboratory Medicine

摘　　要：患儿女,出生6 d 19 h,以“皮肤黄染3 d,发热6 h”于2023年3月31日就诊于重庆大学附属江津医院。4月1日报告血培养危急值:革兰阴性杆菌,经质谱及生化经鉴定为沙门菌属,血清型AF多价(-),Vi(-),考虑为非A~F群沙门菌。传代培养后血清凝集试验结果为:O13,23 Hz,l,w,利用16S rRNA和gyrB基因测序鉴定为肠沙门菌肠道亚种沃兴顿株,与血清学试验相符。患儿经氨苄西林舒巴坦抗感染治疗14 d后病情好转出院。沙门菌鉴定需同时进行细菌生化鉴定和血清学试验,以保证检测准确性,为临床提供可靠的病原学诊断依据。The patient was a 6-day-and-19-hours-old girl.On March 31,2023,she was admitted to Chongqing University JiangJin Hospital with symptoms of yellow skin staining for 3 days and fever for 6 hours.On April 1st,the Medicine Laboratory reported a critical value in blood cultures:Gram-negative bacilli,which were identified as Salmonella through mass spectrometry and biochemical tests.It was classified as non A-F group Salmonella due to negative AF and Vi serotyping results.Subsequent serum agglutination test after subculture showed O13,23 Hz,l,w,and further results by analysis using the sequences of the 16S rRNA and gyrB genes confirmed it as Salmonella enterica subsp.enterica Serovar Worthington Strain,consistent with the serum agglutination test result.After receiving a 14-day course of Ampicillin/Sulbact treatment for infection control,the patient′s health condition improved she was discharged from the hospital.The identification of Salmonella requires simultaneous bacterial biochemical identification and serological tests ser to ensure accurate results and provide reliable basis for etiological diagnosis.

关 键 词：沙门菌属 血清分型 血流感染 

分 类 号：R722.1[医药卫生—儿科]