当代中国人群牙齿可观测特征的多样性研究  

Diversity of Dental Observable Characteristics among Contemporary Chinese Groups

作　　者：罗浩 陈颖洁 杨光睿 Kaustubh Adhikari 夏斌[3] Andrés Ruiz-Linares Miguel Delgado LUO Hao;CHEN Yingjie;YANG Guangrui;Kaustubh ADHIKARI;XIA Bin;Andrés RUIZ-LINARES;Miguel DELGADO(Key Laboratory of Contemporary Anthropology of Ministry of Education and Department of Anthropology and Human Genetics,School of Life Sciences,Fudan University,Shanghai,200438;Faculty of Science,Technology,Engineering&Mathematics,School of Mathematics&Statistics,Open University,London,Britain,MK76AA;School of Stomatology,Peking University,Beijing,100086;Anthropology Division,Faculty of Natural Sciences and Museum,National University of La Plata,La Plata,Argentina,1900)

机构地区：[1]复旦大学生命科学学院现代人类学教育部重点实验室,人类遗传学与人类学系,上海200438 [2]开放大学科学,技术,工程和数学学院,数学与统计学院,英国伦敦MK76AA [3]北京大学口腔医学院,北京100086 [4]拉普拉塔国立大学自然科学及博物馆学院人类学科,阿根廷拉普拉塔1900

出　　处：《基因组学与应用生物学》2024年第1期150-171,共22页Genomics and Applied Biology

基　　金：国家自然科学基金项目(31771393)资助。

摘　　要：本研究基于当代中国人群3D牙齿模型数据,参照拉美人群进化和多样性研究联合会(consortium for the analysis of the diversity and evolution of Latin America,CANDELA)所使用的牙齿特征点标记方法,使用牙齿特征点间的欧几里得线性距离(Euclidean linear distances,ELD)表示的牙齿表型作为牙齿可观测特征的度量,探究个体因素(年龄、性别)和群体因素(民族)对当代中国人群牙齿可观测特征多样性的影响。通过对牙齿标记特征点的典型变量分析(canonical variate analysis,CVA)、交叉验证(cross validation,CV)、主成分分析(principal component analysis,PCA)以及对牙齿表型的Pearson相关性分析和差异分析,本研究发现进化上相近的群体牙齿可观测特征往往更接近。具体来说,汉族的上颌牙齿可观测特征和壮族、苗族较为接近而不同于蒙古族的,而藏族的上、下颌牙齿可观测特征不同于维吾尔族的;南北中汉族牙齿表型的差异具有明确的方向性,下颌牙齿差异比上颌更明显;从性别角度看,男女牙齿表型差异主要体现在尖牙上,男性尖牙平均宽度和高度显著大于女性的;对不同年龄群体的差异分析表明,遗传外因素对牙齿可观测特征的影响主要体现在尖牙、上颌第一磨牙、下颌第一前磨牙上。This study is based on the 3D dental models data of contemporary Chinese groups,and dental landmarking method is used in this study,which is used by the consortium for the analysis of the diversity and evolution of Latin America(CANDELA).Dental phenotypes represented by Euclidean linear distances(ELD)between landmarks in this study are basis of measurement of dental diversity.This study aims to explore the impact of individual factors(age and gender)and population factor(ethnic groups)on the dental diversity among contemporary Chinese groups.The results of canonical variate analysis(CVA),cross validation(CV),principal component analysis(PCA),Pearson correlation analysis and differences analysis showed that the dental observable characteristics of populations which had closer evolutionary relationships were often more similar.Specifically,the dental observable characteristics of upper teeth of Han nationality are closer to those of Zhuang and Miao nationalities but different from that of Mongolian nationality,and the dental observable characteristics of upper and lower teeth of Tibetan nationality are different from those of Uyghur nationality.The differences in dental phenotypes of southern/northern/central Han Chinese were clearly directional,and the differences of mandibular teeth was more obvious than that of maxillary teeth.From the perspective of gender,the differences of dental phenotypes between men and women were mainly reflected in the canines,and the average width and height of male canines were significantly greater than that of female canines.The differences analysis among different age groups showed that the influence of extragenetic factors on the dental observable characteristics was mainly reflected in the canines,maxillary first molars and mandibular first premolars.

关 键 词：当代中国人群 牙齿可观测特征 表型差异 

分 类 号：Q983[生物学—人类学]