心脏移植中应用边缘供心的预后分析  

Prognosis analysis of marginal heart donor in heart transplantation

作　　者：耿俊义 周强[2] 周志明[2] 常峰荣 郭长英[1] Geng Junyi;Zhou Qiang;Zhou Zhiming;Chang Fengrong;Guo Changying(Department of Surgical Intensive Care Unit,Zhengzhou 7th.People’s Hospital,Zhengzhou 450016,China;Department of Heart Transplantation Centre,Zhengzhou 7th.People’s Hospital,Zhengzhou 450016,China)

机构地区：[1]郑州市第七人民医院外科重症监护室,郑州450016 [2]郑州市第七人民医院外科心脏移植中心,郑州450016

出　　处：《中华胸心血管外科杂志》2024年第1期50-54,共5页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：河南省医学科技攻关计划项目(LHGJ20220843)。

摘　　要：目的探讨心脏移植中应用边缘供心患者的预后。方法回顾性纳入郑州市第七人民医院2018年4月至2022年11月期间的连续心脏移植受者和供者的临床资料。根据边缘供心的定义,将受体患者分为常规供心组(117例)和边缘供心组(62例),分析两组患者的心脏移植术前、术后资料。结果边缘供心形成的主要原因是供心冷缺血时间>6 h;术前使用体外膜肺氧合和机械通气更容易接收到边缘供心;心脏移植中利用边缘供心,术后机械通气时间和监护室停留时间增加;使用边缘供心患者的生存率比常规供心患者低,但差异无统计学意义。结论心脏移植中应用边缘供心是解决心脏器官短缺,减少移植等待者死亡的有效方法。Objective To investigate the prognosis of marginal donor heart in heart transplantation.Methods The clinical data of consecutive heart transplant recipients and donors in Zhengzhou 7th.People’s Hospital from April 2018 to November 2022 were retrospectively included.According to the definition of marginal donor hearts,the patients were divided into conventional donor hearts group(117 cases)and marginal donor hearts group(62 cases),the data before and after heart transplantation of the two groups were analyzed.Results The main reason for the formation of marginal donor hearts was the cold ischemia time of donor hearts>6 h;it was easier to receive marginal donor hearts with ECMO and MV before operation;the use of marginal donor hearts in heart transplantation increased postoperative mechanical ventilation time,surgical post-intensive care unit length of stay;patients with marginal donors had lower survival than conventional donors,but did not produce a significant difference in survival after heart transplantation.Conclusion The application of marginal donor heart in heart transplantation is an effective method to solve the shortage of heart organs and reduce the death of transplant waiting persons.

关 键 词：心脏移植 边缘供心 预后分析 

分 类 号：R654.2[医药卫生—外科学]