基于Au-Ag合金的EC-SERS光谱监测多巴胺氧化还原反应  

Probing Dopamine Redox Reactions Based on Au-Ag Alloys and EC-SERS

作　　者：王康[1] 刘官 张磊[1] WANG Kang;LIU Guan;ZHANG Lei(Nanjing University of Posts and Telecommunications,Nanjing 210000,China)

机构地区：[1]南京邮电大学,江苏南京210000

出　　处：《广州化学》2024年第1期33-37,I0002,共6页Guangzhou Chemistry

基　　金：江苏省自然科学基金面上项目(BK20211271)。

摘　　要：采用一锅法即柠檬酸盐还原法合成了大小形貌均匀的Au-Ag纳米颗粒,接着利用咖啡环效应,在ITO玻璃表面固定Au-Ag纳米颗粒,制备出了具有表面增强拉曼散射(SERS)响应的活性基底,该基底表现出优异的SERS重现性与均一性。将其作为EC-SERS的工作电极,通过电化学和SERS相结合的方法来检测Au-Ag表面多巴胺(苯酚)和多巴胺(苯醌)的光谱性质,发现可采用H2O2和GSH调制其在1270、1335和1455 cm^(-1)处的SERS光谱强度。最后通过恒电位法探究了多巴胺(DA)在电极上氧化还原的电位依赖性变化,为研究其氧化还原性质提供了新的依据。The citrate reduction method was used to synthesize Au-Ag nanoparticles of uniform size and shape,followed by the preparation of active substrates with surface-enhanced Raman scattering(SERS)response by immobilizing Au-Ag nanoparticles on ITO glass surfaces using the coffee ring effect.Using it as a working electrode for EC-SERS,we examined the spectral properties of dopamine(phenol)and dopamine(benzoquinone)on the Au-Ag surface by a combined electrochemical and SERS methods and found that H2O2 and GSH could be used to modulate their SERS spectral intensities at 1270,1335 and 1455 cm^(-1).Finally,the potential-dependent changes in the redox of dopamine(DA)at the electrode were investigated by the constant potential method,providing a new basis for the study of its redox properties.

关 键 词：电化学-表面增强拉曼散射 多巴胺 氧化还原 表面增强拉曼散射 

分 类 号：O656.6[理学—分析化学]