妊娠期碘营养评价指标研究进展  

Progress in the study of iodine nutrition evaluation indicators during pregnancy

作　　者：聂骄阳 王琛琛[3] 张玲[4] Nie Jiaoyang;Wang Chenchen;Zhang Ling(Department of Labor Hygiene and Environmental Health,School of Public Health,Xinjiang Medical University,Urumqi 830011,China;School of Public Health and Health Management,Henan Medical College,Zhengzhou 451191,China;Institute of Environmental Health and Endemic Disease,Center for Diseases Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi 830002,China;Office of the Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi 830002,China)

机构地区：[1]新疆医科大学公共卫生学院劳动卫生与环境卫生学教研室,乌鲁木齐830011 [2]河南医学高等专科学校公共卫生与健康管理学院,郑州451191 [3]新疆维吾尔自治区疾病预防控制中心环境健康与地方病防治所,乌鲁木齐830002 [4]新疆维吾尔自治区疾病预防控制中心办公室,乌鲁木齐830002

出　　处：《中华地方病学杂志》2023年第12期1024-1028,共5页Chinese Journal of Endemiology

基　　金：国家自然科学基金(82260648)。

摘　　要：碘作为人体合成甲状腺激素的主要原料,与甲状腺功能间呈现"U"形曲线关系,碘缺乏和过量均可能造成甲状腺功能障碍,损害人体健康。我国曾是世界上碘缺乏病广泛流行的国家之一,1995年开始实施全民食盐加碘政策之后,居民碘营养状况得到了大幅度改善,碘缺乏病消除目标已基本实现,但仍存在易感人群(孕妇、哺乳期妇女和婴儿)碘营养缺乏的情况。妊娠期是妇女的特殊生理阶段,为满足自身及胎儿的碘需求,妊娠期妇女碘需求量比非妊娠期妇女增加约50%。世界卫生组织/联合国儿童基金会/国际控制碘缺乏病理事会(WHO/UNICEF/ICCIDD)建议使用尿碘浓度(UIC)评价妊娠期碘营养状况,UIC在150~<250μg/L为碘适宜,但评价妊娠期碘营养状况的最佳方法仍存在争议。随着社会经济水平和人们健康意识的提高,尤其在妊娠期等特殊阶段,人们对个体碘营养状况更加重视。因此,探寻有效的妊娠期碘营养评价指标变得愈发重要。Iodine,as the main raw material for the synthesis of thyroid hormones in the body,exhibits a U-shaped curve relationship with thyroid function.Both iodine deficiency and excess may cause thyroid dysfunction and damage human health.China was once one of the countries where iodine deficiency were widely prevalent in the world.Since the implementation of universal salt iodization in 1995,the iodine nutritional status in China has been greatly improved,and the goal of eliminating iodine deficiency disorders has been basically achieved.However,there is still a state of inadequate iodine nutrition among susceptible populations(pregnant women,breastfeeding mothers and infants).Pregnancy is a special physiological stage for women,and in order to meet the iodine needs of themselves and their fetuses,the iodine requirement of pregnant women increases by about 50%compared to non-pregnant women.WHO/UNICEF/ICCIDD suggest using urinary iodine concentration(UIC)to evaluate iodine nutritional status during pregnancy,with UIC of 150-<250μg/L is considered suitable for iodine nutrition,but the best method for evaluating iodine nutrition status during pregnancy is still controversial.With the improvement of socio-economic level and people's health awareness,especially during special stages such as pregnancy,people pay more attention to individual iodine status.Therefore,the investigation of reliable indicators for evaluating iodine nutrition during pregnancy has gained increasing significance.

关 键 词：尿碘 妊娠期 评价指标 碘营养状况 

分 类 号：R715.3[医药卫生—妇产科学]