张声生“调态消癥”辨治慢性萎缩性胃炎及胃癌前病变创新思路构建及运用  

Construction and application of ZHANG Shengsheng's innovative ideas to differentiate and treat chronic atrophic gastritis and precancerous lesions of gastric cancer through‘Tiaotai Xiaozheng'

作　　者：李丹艳 赵鲁卿[1] 丁宁[2] 王阿玲 张声生(指导)[1] LI Danyan;ZHAO Luqing;DING Ning;WANG Aling;ZHANG Shengsheng(Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Capital Medical University,Beijing 100010,China)

机构地区：[1]首都医科大学附属北京中医医院,北京100010 [2]首都医科大学,北京100010

出　　处：《中华中医药杂志》2024年第1期229-234,共6页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家中医药管理局中医传承与创新“百千万”人才工程(岐黄学者)国家中医药领军人才支撑计划项目(No.国中医药人教函[2021]203号);国家自然科学基金青年科学基金项目(No.82004332)。

摘　　要：慢性萎缩性胃炎(CAG)及胃癌前病变(PLGC)是消化系统的常见病及疑难病,深化对CAG及PLGC病因病机的认识既能丰富中医理论研究体系,更有助于指导临床治疗。张声生教授临证论治CAG及PLGC经验丰富,总结本病“五态一癥”病机学说,即“虚、浊、滞、瘀、毒、癥”。其中脾胃虚弱是根本病机,浊、滞、瘀、毒交结是CAG及PLGC重要的病变状态,癥是疾病的靶标。基于此病机,张声生教授系统总结“调态消癥”理论,包括“调虚态、调浊态、调滞态、调瘀态、调毒态、消癥积”,以期对本病的辨治论治提供新的思路。Chronic atrophic gastritis(CAG)and precancerous lesions of gastric cancer(PLGC)are common and difficult diseases of the digestive system.Deepening the understanding of the etiology and pathogenesis of CAG and PLGC can not only enrich the theoretical research system of traditional Chinese medicine,but also help to guide clinical treatment.Professor ZHANG Shengsheng has rich experience in the treatment of CAG and PLGC,and summarizes the key pathogenesis of CAG and PLGC as‘Five main states and key Zheng masses',namely'deficiency,turbidity,stagnation,stasis,toxin and Zheng masses'.Weakness of the spleen and stomach is the fundamental pathogenesis;Turbidity,stagnation,stasis and toxins are the important pathological conditions of CAG and PLGC;Zheng masses is the target of the disease.Based on this pathogenesis,professor ZHANG Shengsheng puts forward six methods of syndrome differentiation and treatment,namely Five main states and key Zheng masses,including'regulating deficiency state,regulating turbidity state,regulating stagnation state,regulating stasis state,regulating toxin state and eliminating Zheng masses',to provide new thinking for the syndrome differentiation and treatment of this disease.

关 键 词：慢性萎缩性胃炎 胃癌前病变 病机 五态一癥 调态消癥 

分 类 号：R259[医药卫生—中西医结合] R249[医药卫生—中医内科学]