五行音乐联合八段锦治疗轻中度抑郁和焦虑障碍的临床研究  

Clinical study of five-element music combined with Baduanjin in the treatment of mild to moderate anxious and depressive disorder

作　　者：曹云松[1] 韩振蕴 胡文悦 林景峰 王振亦 常泽 王育纯 马华萍 CAO Yunsong;HAN Zhenyun;HU Wenyue;LIN Jingfeng;WANG Zhenyi;CHANG Ze;WANG Yuchun;MA Huaping(Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China;Shenzhen Hospital(Longgang),Beijing University of Chinese Medicine,Shenzhen 518172,China;Beijing University of Chinese Medicine,Beijing 100029,China;Affiliated Mental Health Center,School of Medicine,Zhejiang University,Hangzhou 310000,China)

机构地区：[1]北京中医药大学东方医院,北京100078 [2]北京中医药大学深圳医院(龙岗),深圳518172 [3]北京中医药大学,北京100029 [4]浙江大学医学院附属精神卫生中心,杭州310000

出　　处：《中华中医药杂志》2024年第1期505-509,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：深圳市“医疗卫生三名工程”项目(No.SZZYSM202105010);浙江省中医药科技计划项目(No.2021ZB231)。

摘　　要：目的:观察中医养生疗法(五行音乐联合八段锦)对气郁化火型轻中度焦虑抑郁障碍的临床效果。方法:收集2018年8月至2019年11月就诊于北京地区三家中医医院的气郁化火型轻中度抑郁和焦虑障碍患者150例,根据患者治疗方案不同分为对照组(盐酸舍曲林片50mg1次/d+丹栀逍遥散加减)和治疗组(对照组治疗+五行音乐联合八段锦疗法),各75例,疗程为8周,分别于治疗前、治疗第4周、第8周评定汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)评分。结果:两组治疗前后HAMD、HAMA量表评分及有效率比较差异有统计学意义;两组治疗前后HAMD评分因子(焦虑/躯体化、认识障碍、阻滞、睡眠障碍)、HAMA评分因子(躯体性焦虑、精神性焦虑)下降程度比较差异均有统计学意义;治疗组轻度抑郁患者第8周HAMD评分较对照组显著下降(P<0.05)。结论:中医养生疗法(五行音乐联合八段锦)在改善轻度抑郁障碍方面有一定的疗效优势,具有一定的临床意义。Objective:To observe the clinical efficacy of traditional Chinese medicine(TCM)health therapy(fiveelement music combined with Baduanjin)on mild to moderate anxious and depressive disorder of qi-fire stagnation type.Methods:A prospective cohort study was used to collect patients with mild to moderate anxious and depressive disorder of qi-fire stagnation type in 3 TCM hospitals in Beijing from August 2018 to November 2019.According to the different treatment regimens of patients,they were divided into control group(sertraline hydrochloride tablet 50 mg 1 time/d+Danzhi Xiaoyao Powder)and treatment group(control group treatment+five-element music combined with Baduanjin),with 75 cases in each group,and the course of treatment was 8 weeks.HAMD and HAMA scores were assessed before treatment,at week 4th and 8th respectively.Results:There were statistically significant differences in the HAMD and HAMA scale scores,as well as the response rates,between the two treatment groups before and after treatment.The degree of decrease in HAMD factor scores(anxiety/somatization,cognitive impairment,retardation,sleep disturbance)and HAMA factor scores(somatic anxiety,psychic anxiety)also showed statistically significant differences between the two groups.In comparison to the control group,patients with mild depression in the treatment group showed a significant decrease in HAMD score after 8 weeks(P<0.05).Conclusion:TCM health therapy(five-element music combined with Baduanjin)has certain therapeutic advantages in improving mild depressive disorder and has clinical reference value.

关 键 词：八段锦疗法 疗效评价 轻中度抑郁与焦虑障碍 五行音乐疗法 

分 类 号：R277.7[医药卫生—中医学]