经甲舌膜病灶内糖皮质激素注射对喉接触性肉芽肿的疗效观察  

Clinical Observation of the Effect of Glucocorticoid Injection Through the Thyrohyoid Membrane on Laryngeal Contact Granuloma

作　　者：邵永良 韩琳[2] 杨泽垠 陈坤 SHAO Yongliang;HAN Lin;YANG Zeyin;CHEN Kun(Department of Otolaryngology,Head and Neck Surgery,the People's Hospital of Shijiazhuang City,Shijiazhuang 050031,China;Department of Otolaryngology,Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang 050000,China)

机构地区：[1]石家庄市人民医院耳鼻咽喉头颈外科,石家庄050031 [2]石家庄市中医院耳鼻喉科,石家庄050000

出　　处：《临床误诊误治》2023年第12期102-104,139,共4页Clinical Misdiagnosis & Mistherapy

基　　金：河北省卫生计生委项目(20160002);石家庄市科技局项目(201200793)。

摘　　要：目的探讨经甲舌膜穿刺病灶内糖皮质激素注射在喉接触性肉芽肿(LCG)治疗中的效果。方法选取2020年1月—2022年1月收治的88例LCG,根据治疗方法的不同分为对照组52例(应用药物抑酸疗法)和观察组36例(在对照组治疗基础上联合经甲舌膜病灶内糖皮质激素注射治疗),全部病例随访12个月,比较2组治疗效果和治愈时间。结果2组临床总有效率比较无差异(P>0.05),但观察组治愈率高于对照组(P<0.05)。观察组治愈时间为(91.62±4.00)d短于对照组的(126.44±5.50)d(P<0.05)。结论经甲舌膜病灶内糖皮质激素注射联合抑酸疗法治疗LCG的效果显著,操作简单易行,成功率高,可显著缩短疗程。Objective To investigate the effect of glucocorticoid injection by puncture through thyrohyoid membrane in the treatment of laryngeal contact granuloma(LCG).Methods A total of 88 patients with LCG treated from January 2020 to January 2022 were selected and divided into control group(treated with acid suppression therapy,n=52)and observation group(treated with glucocorticoid injection by puncture through thyrohyoid membrane on the basis of control group,n=36)according to different treatment methods.All cases were followed up for 12 months,and the therapeutic effect and duration of cure of the two groups were compared.Results There was no difference in the total effective rate between the two groups(P>0.05),but the cure rate of the observation group was higher than that of the control group(P<0.05).The duration of cure of observation group was(91.62±4.00)d,which was shorter than that of control group[(126.44±5.50)d](P<0.05).Conclusion Glucocorticoid injection by puncture through thyrohyoid membrane combined with acid suppressive therapy is more effective for LCG,with operability,feasibility,and a high success rate,which can significantly shorten the course of treatment.

关 键 词：肉芽肿 喉 甲舌膜穿刺 糖皮质激素 抑酸疗法 病因 联合治疗 治疗结果 治愈时间 

分 类 号：R767.19[医药卫生—耳鼻咽喉科]