Embosphere微球血管内栓塞治疗大咯血的疗效分析  

Analysis of therapeutic efficacy of endovascular embolization using Embosphere microsphere in the treatment of massive hemoptysis

作　　者：徐红豆 杨亮 姚双龙 胡世兵 XU Hongdou;YANG Liang;YAO Shuanglong;HU Shibing(Department of Interventional Radiology,Gaochun People's Hospital,Nanjing 211300,China)

机构地区：[1]南京市高淳人民医院介入放射科,江苏南京211300

出　　处：《实用放射学杂志》2024年第1期107-110,共4页Journal of Practical Radiology

摘　　要：目的探讨在支气管动脉栓塞术(BAE)中应用Embosphere微球治疗大咯血的安全性及有效性,Cox回归模型分析复发的影响因素。方法选取行BAE治疗大咯血的患者90例,所有栓塞材料均为Embosphere,统计分析24h即刻止血率、临床成功率及预后因素。结果24h即刻止血率为94.4%(85/90),临床成功率为56.7%(51/90)。患者术后6个月、1年和2年的累积无咯血复发控制率分别为81%、78%和57%。Cox回归模型分析显示影响咯血复发的危险因素为长期咯血史、肺癌、结核病和肺毁损。结论Embosphere微球是一种安全、有效的栓塞颗粒,在控制咯血方面具有良好效果,长期咯血史、肺癌病史、结核病和肺毁损是咯血复发的危险因素。Objective To investigate the safety and efficacy of Embosphere microsphere in the treatment of massive hemoptysis during bronchial arterial embolization(BAE).To analyze the factors influencing the recurrence by Cox regression model.Methods Ninety patients with massive hemoptysis who underwent BAE using Embosphere microsphere were included.The immediate hemostasis rate within 24 hours,clinical success rate and prognostic factors were statistically analyzed.Results The immediate hemostasis rate within 24 hours was 94.4%(85/90).The clinical success rate was 56.7%(51/90).Cumulative hemoptysis-free recurrence control rates at 6 months,1 year and 2 years postoperative were 81%,78%and 57%,respectively.Cox regression model analysis showed that the variables associated with recurrence were long-term hemoptysis,lung cancer,tuberculosis and lung destruction.Conclusion Embosphere microsphere are safe and effective embolic particles in the treatment of massive hemoptysis during BAE.Risk factors for hemoptysis recurrence include long-term hemoptysis,lung cancer,tuberculosis and lung destruction.

关 键 词：大咯血 危险因素 Embosphere微球 

分 类 号：R441.7[医药卫生—诊断学] R815[医药卫生—临床医学]