GRASP自由呼吸动态对比增强MRI与常规BH-VIBE序列在肺癌图像质量中的对比研究  

Comparison of GRASP free-breathing dynamic contrast-enhanced MRI and traditional BH-VIBE sequences in the imaging quality of lung cancer

作　　者：余景火 储蕾 丁雪怡 孙宜楠 杨擎[1] 朱娟[1] YU Jinghuo;CHU Lei;DING Xueyi;SUN Yi'nan;YANG Qing;ZHU Juan(Imaging Center,Anqing Municipal Hospital,Anqing,Anhui Prooince 246003,China)

机构地区：[1]安庆市立医院影像中心,安徽安庆246003

出　　处：《实用放射学杂志》2024年第1期123-126,共4页Journal of Practical Radiology

基　　金：皖南医学院基金项目(JXYY202235);安徽医科大学校科研基金项目(2017xkj073)。

摘　　要：目的评估自由呼吸状态下黄金角径向稀疏平行采样(GRASP)技术在肺癌MR图像质量中的临床实用价值。方法使用大口径3.0T MR扫描仪采集30例经CT筛查并确诊肺癌患者的图像信息,所有患者均先执行常规笛卡尔屏气容积内插(BH-VIBE)扫描,然后行基于GRASP技术的自由呼吸动态对比增强磁共振成像(DCE-MRI)扫描,最后再行BH-VIBE扫描方案。阅片由2位经验丰富的胸部放射科医生独立评估(内容包括总体图像质量、病变轮廓、伪影等级、诊断信心),以患者同时期CT图像作为参照,同时对各序列信息进行盲法处理。结果GRASP序列由于能够有效消除呼吸及心脏大血管搏动等运动伪影的干扰,在总体图像质量、病变轮廓、伪影等级及诊断信心方面与BH-VIBE图像均有明显统计学差异(P<0.01),能更精准地显示肿瘤边界及图像细节。结论自由呼吸高时空分辨率GRASP技术较传统BH-VIBE扫描有着更优的图像质量,是对肺部病变进行高分辨率成像的一种可靠方法。Objective To evaluate the clinical practical value of the golden angle radial sparse parallel(GRASP)technology in the MR imaging quality of lung cancer under free-breathing state.Methods The imaging data of 30 lung cancer patients diagnosed with CT screening were collected by using a large-aperture 3.OT MR scanner.All patients underwent routine Cartesian breath-hold volume interpolation(BH-VIBE)scanning,then free-breathing dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)scanning based on GRASP technology,and another repetitive BH-VIBE scanning.The MR imaging quality was independently evaluated by two experienced thoracic radiologists including overall image quality,lesion outline,artifact grade and diagnostic confidence,meanwhile,the CT images of the patient at the same time were used as a reference.The sequence information on MR images was also processed blindly.Results The GRASP sequence could effectively eliminate the interference of motion artifacts such as respiration and cardiac large vessel beats,and the image quality,lesion outline,artifact grade,and diagnostic confidence of the GRASP sequence were significantly better than the BH-VIBE(P<O.O1).The image quality of the GRASP sequence was more satisfactory with clearer tumor boundary and more details.Conclusion Free-breathing high-temporal-spatial resolution GRASP technology has better image quality than traditional BH-VIBE scanning,and it is a reliable method for high-resolution imaging of lung cancer.

关 键 词：动态对比增强磁共振成像 自由呼吸 黄金角径向稀疏并行采样 肺癌 

分 类 号：R445.2[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]