基于Neo4j探究程红亮教授针灸治疗中风后吞咽障碍临床规律  

Exploring professor Cheng Hongliang’s clinical patterns in acupuncture treatment of dysphagia post-stroke using neo4j

作　　者：吴安琪 周冰原 程红亮[2] 胡培佳[3] 张闻东[2] Wu Anqi;Zhou Bingyuan;Cheng Hongliang;Hu Peijia;Zhang Wendong(Graduate School,Anhui University of Chinese Medicine,Hefei 230038,Anhui,China;Department of Encephalopathy,Second Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230061,Anhui,China;Acupuncture and Moxibustion Clinical Research Institute,Anhui University of Chinese Medicine,Hefei 230038,Anhui,China)

机构地区：[1]安徽中医药大学研究生院,安徽合肥230038 [2]安徽中医药大学第二附属医院脑病五科,安徽合肥230061 [3]安徽中医药大学针灸临床研究所,安徽合肥230038

出　　处：《右江民族医学院学报》2024年第1期116-123,共8页Journal of Youjiang Medical University for Nationalities

基　　金：安徽省重点研究与开发计划项目(2022e07020026);安徽省临床医学研究转化专项(202304295107020123);安徽省卫生健康委科研重点项目(AHWJ2021a020)。

摘　　要：目的基于Neo4j知识图谱技术探究程红亮教授针灸治疗中风后吞咽障碍临床规律。方法收集568份安徽中医药大学第二附属医院脑病五科2019年6月至2023年6月门诊的中风后吞咽障碍患者针灸诊疗记录,运用Neo4j 3.5.25图数据库生成证型总体关系图谱,基于Python 3.8.6进行频数统计分析,利用PHP 5.4程序代码进行腧穴关联规则分析,并在Neo4j中绘制腧穴关联规则知识图谱,运用Cypher语句查询目标证型关联度较高的关系并输出得到证型聚类知识图谱。结果共涉及中医证型7种,分布频率百分比≥20%的症状有18个,频率≥20%的腧穴有19个,腧穴归经分布次数较多的有任脉、足少阳胆经、经外奇穴、督脉、足阳明胃经、足太阴脾经。提升度较高的关联组合由以下腧穴组成:手三里、外关、曲池、阳陵泉、大钟、气海、血海等,得到证型聚类知识图谱。结论程红亮教授提出“咽为经脉之所聚”理论,认为针灸治疗中风后吞咽障碍当以“辨经论治”为核心,确立了以任、督二脉为主,结合不同经脉组穴的取穴思路。Objective This study employs Neo4j knowledge graph technology to investigate the clinical patterns in professor Cheng Hongliang’s acupuncture treatment of dysphagia after stroke.Methods We collected a total of 568 records of acupuncture and moxibustion diagnosis and treatment of patients with post-stroke dysphagia in the Department of Encephalopathy,Second Affiliated Hospital of Anhui University of Chinese Medicine from June 2019 to June 2023.Neo4j 3.5.25 graph database was used to generate a comprehensive relationship graph of syndrome types.Based on Python 3.8.6,frequency statistical analysis was carried out.and PHP 5.4 program code was used to analyze the association rules of acupoints,and the knowledge graph of acupoint association rules was drawn in Neo4j.Cypher statements were used to query the relationship with high correlation degree of target syndrome type and output the knowledge graph of syndrome clustering.Results Among them,a total of 7 traditional Chinese medicine syndromes were involved.There were 18 symptoms with a distribution frequency of≥20%,and 19 acupoints with a frequency of≥20%.Noteworthy acupoints based on meridian distribution were Ren Channel,Gallbladder Channel of Foot Shaoyang,Extraordinary Points,Governor Channel,Stomach Channel of Foot Yangming,and Spleen Channel of Foot Taiyin.Acupoint combinations with higher lifting degrees included Shousanli(LI10),Waiguan(SJ5),Quchi(LI11),Yanglingquan(GB34),Dazhong(KI4),Qihai(RN6),Xuehai(SP10),etc.,and the knowledge graph of syndrome type clustering is obtained.Conclusion Professor Cheng Hongliang’s theory,“The pharynx is the gathering place of the channels”,emphasizes the core of“diagnosing channels for treatment”.He has established a treatment approach primarily focusing on the Ren and Governor channels,combined with the strategy of selecting acupoints based on different meridian groups.

关 键 词：知识图谱 针灸 中风后吞咽障碍 临床规律 程红亮 

分 类 号：R256.623[医药卫生—中医内科学]