人偏肺病毒感染研究进展  

Research Progress on Human Metapneumovirus Infection

作　　者：麻粉莲[1] 郑丽舒[1] MA Fenlian;ZHENG Lishu(National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,NHC Key Laboratory of Medical Virology and Viral Diseases,National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases(NITFID),Beijing 100052,China)

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,国家卫生健康委员会医学病毒与病毒病重点实验室,传染病溯源预警和智能决策全国重点实验室,北京100052

出　　处：《病毒学报》2024年第1期133-139,共7页Chinese Journal of Virology

摘　　要：人偏肺病毒(Human metapneumovirus,HMPV)是急性呼吸道感染的主要病原之一,可感染所有人群的上呼吸道和下呼吸道,感染后多引起咳嗽、发烧、鼻塞和呼吸短促等症状,在婴幼儿、老年人和免疫功能低下者等易感人群中可致支气管炎和肺炎等严重疾病。目前HMPV尚无疫苗和特效药物,治疗措施多为对症支持治疗。2023年1月至4月HMPV在美国检出率出现高峰,短时间内出现大量病例,引起了社会各界的广泛关注。本文将就HMPV病原学特点、流行特点、HMPV感染的临床特征及发病机制等方面的的研究现状进行简单综述,为HMPV感染的科学预防和控制提供参考。Human metapneumovirus(HMPV)is a leading cause of acute respiratory tract infection,can cause upper and lower respiratory disease in people of all ages.Symptoms commonly associated with HMPV include cough,fever,nasal congestion,and shortness of breath,clinical symptoms of HMPV infection may progress tobronchitis or pneumonia among children,elderly,and immunocompromised patients.Currently,there is no specific antiviral therapy to treat HMPV and no vaccine to prevent HMPV.Medical care is supportive.From January to April 2023,the detection rate of HMPV reached its peak in the United States,with a large number of cases occurring in a short period of time,which has attracted widespread attention from all sectors.This paper briefly summarizes the previous studies and reports on the molecular virology,epidemiology,clinical features and pathogenesis of HMPV,so as to provide reference for scientific prevention and control of HMPV infection.

关 键 词：人偏肺病毒 感染 流行特点 

分 类 号：R373.1[医药卫生—病原生物学]