糖皮质激素在病毒性肺炎的合理应用  

Rational use of glucocorticoids in viral pneumonia

作　　者：朱蕾 ZHU Lei(Department of Respiratory and Critical Care Medicine,Huadong Hospital Affiliated to Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华东医院呼吸与危重医学科,上海200040

出　　处：《实用医院临床杂志》2024年第2期5-7,共3页Practical Journal of Clinical Medicine

基　　金：国家自然科学基金面上项目(编号:8207DD75)。

摘　　要：病毒性肺炎主要表现为急性间质性肺炎,部分进展为急性呼吸窘迫综合征,常需应用糖皮质激素(激素)抑制炎症反应,改善病情;但合理应用激素的指征、时机,以及激素的类型、剂量、给药时间、疗程、疗效和负效应的评价皆无明确依据。本文主要基于生物学和生理学分析对激素在病毒性肺炎中的应用进行分析和总结。Viral pneumonia primarily appears as acute interstitial pneumonia. Some cases develop to acute respiratory distress syndrome. Thus, it is often necessary to apply glucocorticoids (hormones) to decrease the inflammatory response and alleviate the situation. However, there is no clear basis for the indications and timing of rational use of hormones as well as hormone type, dosage, administration time, course of treatment, and evaluation of efficacy and negative effects. This article analyzes and summaries the use of the hormones in viral pneumonia mainly based on biological and physiological studies. It wishes to provide a better reference for clinical practice.

关 键 词：急性间质性肺炎 糖皮质激素 生物学分析 生理学分析 

分 类 号：R563.13[医药卫生—呼吸系统]