宣肺止咳法治疗风邪犯肺型儿童变应性咳嗽的近期疗效及远期复发率观察  

Short-term Efficacy of Dispersing Lung And Relieving Cough Method in Treatment of Allergic Cough in Children with Wind-evil Lung-invading Syndrome and Effect of Long-term Recurrence Rate

作　　者：李曼玲 甘婷 陈帅[3] LI Maning;GAN Ting;CHEN Shuai(Department of Pediatrics,Zhengzhou Institute of Industrial Application Technology,Xinzheng 451100,Henan,China;Clinical Basic Teaching and Research Office of Zhengzhou Institute of Industrial Application Technology,Xinzheng 451100,Henan,China;The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan,China)

机构地区：[1]郑州工业应用技术学院儿科教研室,河南新郑451100 [2]郑州工业应用技术学院临床基础教研室,河南新郑451100 [3]郑州大学第一附属医院,河南郑州450052

出　　处：《中华中医药学刊》2024年第1期100-103,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药行业科研项目(20197758033);河南省医学科技攻关联合共建项目(LHGJ20210329);河南省医学教育研究项目(wjlx2022205)。

摘　　要：目的探讨宣肺止咳法治疗风邪犯肺型儿童变应性咳嗽的近期疗效及远期复发率的影响。方法选择2021年1月—2021年12月120例中医辨证为风邪犯肺型变应性咳嗽的患儿作为研究对象,采用随机数字法平均分为观察组与对照组:对照组患儿给予布地奈德雾化吸入治疗,观察组在对照组基础上联合宣肺止咳法治疗。于治疗前、治疗1周及2周后比较两组中医证候积分及临床疗效差异,并随访6个月比较两组患儿的复发情况。结果观察组总有效率明显高于对照组(P<0.05)。随着治疗时间延长,两组患儿主症、次症及总积分均逐渐降低(P<0.05);治疗1周及2周后观察组主症、次症及总积分均低于对照组(P<0.05)。随着治疗时间延长,两组患儿血清总免疫球蛋白E(Immunoglobulin E,IgE)及嗜酸粒细胞数均逐渐降低(P<0.05);治疗后1个周及2个周观察组血清总IgE及嗜酸粒细胞数均低于对照组(P<0.05)。观察组治疗后3个月及6个月复发率均低于对照组(P<0.05)。结论宣肺止咳法治疗风邪犯肺型儿童变应性咳嗽有更好的临床疗效,更快改善患儿咳嗽症状,更好降低气道炎性反应,且大大降低了远期复发率,值得临床应用。Objective To investigate the short-term effect of dispersing lung and relieving cough therapy on allergic cough in children with wind invading lung syndrome and the influence of long-term recurrence rate.Methods A total of 120 children who were diagnosed as allergic cough due to wind invading lung according to TCM syndrome differentiation from January 2021 to December 2021 were selected as the research subjects and equally divided into the observation group and the control group by using the random number method.The children in the control group were treated with aerosol inhalation of budesonide,while those in the observation group were treated with the method of dispersing lung Qi and relieving cough based on the control group.The differences of TCM syndrome scores and clinical efficacy between the two groups were compared before treatment,1 and 2 weeks after treatment.Besides,the recurrence situations of the two groups were compared after a follow-up of 6 months.Results The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).With the prolongation of treatment time,the main symptoms,secondary symptoms and total scores of children in the two groups were gradually reduced(P<0.05).The main symptoms,secondary symptoms and total scores in the observation group were lower than those in the control group 1 and 2 weeks after treatment(P<0.05).With the prolongation of treatment time,the total serum IgE and eosinophil numbers of children in the two groups were gradually decreased(P<0.05).The total serum IgE and eosinophils in the observation group were lower than those in the control group 1 and 2 weeks after treatment(P<0.05).The recurrence rates in the observation group were lower than those in the control group 3 and 6 months after treatment(P<0.05).Conclusion The method of dispersing lung and relieving cough has better clinical efficacy in the treatment of allergic cough in children with wind invading lung syndrome,which can improve the cough symptoms of childr

关 键 词：宣肺止咳法 风邪犯肺型 儿童 变应性咳嗽 疗效 复发率 

分 类 号：R256.11[医药卫生—中医内科学]