外周血内PCT、CRP及血常规指标在AECOPD患者病情诊断及预后中的应用价值  

Application of PCT,CRP and Routine Blood Indexes in Peripheral Blood in Diagnosis and Prognosis of Patients with AECOPD Value

作　　者：潘可杰 PAN Kejie(Department four of Internal Medicine,Wuwei People's Hospital,Wuhu Anhui 238300)

机构地区：[1]无为市人民医院内四科,安徽芜湖238300

出　　处：《智慧健康》2023年第30期48-52,共5页Smart Healthcare

摘　　要：目的探讨血内PCT、CRP及血常规指标在AECOPD患者病情诊断及预后中的应用价值。方法选取2020年1月—2022年3月收治的80例AECOPD患者作为研究对象,接受相同治疗方式治疗后,按其病史、体征、各项辅助检查和《慢性阻塞性肺疾病急性加重(AECOPD)诊治中国专家共识(2014年修订版)》中相应标准综合判定病情,将其分轻度组(21例)、中度组(32例)、重度组(27例),再纳入同时期到院体检健康者30例作为对照组,各组均接受血内PCT、CRP、血常规检查,用q检验(Newman-Keuls法)比较每两组之间PCT、CRP、血常规指标,用Spearman相关系数判定PCT、CRP、WBC与AECOPD患者病情之间的关系,分析此三项指标检测对AECOPD患者病情诊断和疾病预后方面的评估意义。结果重度组PCT、CRP、WBC指标高于对照组、轻度组、中度组,中度组PCT、CRP、WBC指标高于轻度组、对照组,轻度组PCT、CRP、WBC指标高于对照组(P<0.05)。AECOPD患者治疗后PCT、CRP、WBC指标低于治疗前(P<0.05);根据ROC发现,PCT特异度、敏感度为0.512、0.615;CRP特异度、敏感度0.561、0.921;WBC特异度、敏感度0.661、0.658;联合检测特异度、敏感度0.826、0.899(P<0.01)。结论PCT、CRP、WBC指标与AECOPD病情之间呈正相关,病情越严重,PCR、CRP、WBC指标也就更高,临床可通过检测PCT、CRP指标评估AECOPD患者病情状况和预后。Objective To investigate the application value of PCT,CRP and blood routine indexes in the diagnosis and prognosis of patients with AECOPD.Methods A total of 80patients with AECOPD admitted from January 2020 to March 2022 were selected as the study subjects.After receiving the same treatment,the patients were treated according to their medical history,signs,various auxiliary examinations and the Chinese Expert Consensus on the Diagnosis and Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD)(2014).The patients were divided into mild group(21 cases),moderate group(32 cases)and severe group(27 cases),and then included 30 healthy patients who came to the hospital for physical examination during the same period as the control group.All groups received blood PCT,CRP and routine blood examination,q test(Newman-Keuls method)was used to compare PCT,CRP and blood routine indexes between the two groups,and Spearman correlation coefficient was used to determine the relationship between PCT,CRP and WBC and the disease conditions of AECOPD patients,and the significance of these three indexes in the evaluation of the diagnosis and prognosis of AECOPD patients was analyzed.Results The PCT,CRP and WBC indexes of severe group were higher than those of control group,mild group and moderate group;the PCT,CRP and WBC indexes of moderate group were higher than those of mild group and control group;the PCT,CRP and WBC indexes of mild group were higher than those of control group(P<0.05).The PCT,CRP and WBC indexes of AECOPD patients after treatment were lower than those before treatment(P<0.05);According to ROC,PCT specificity and sensitivity were 0.512 and 0.615;CRP specificity and sensitivity were 0.561 and 0.921;WBC specificity,sensitivity 0.661,0.658;The specificity and sensitivity of combined detection were 0.826 and 0.899(P<0.01).Conclusion PCT,CRP and WBC were positively correlated with AECOPD.The more severe the disease was,the higher the PCR,CRP and WBC indexes were.Clinical assessment of the dise

关 键 词：AECOPD CRP PCT 病情 预后 

分 类 号：R563.9[医药卫生—呼吸系统]