肉眼血尿对尿常规AVE752型尿干化学分析的影响及处理措施探讨  

The Influence of Macroscopic Hematuria on AVE752 Urinary Dry Chemistry Analysis and Its Treatment Measures

作　　者：张井泉 江丽明 陈伟德 王尔莉 ZHANG Jing-quan;JIANG Li-ming;CHEN Wei-de;WANG Er-li(Zhangzhou Hospital,Fujian Zhangzhou 363000)

机构地区：[1]漳州市医院,福建漳州363000

出　　处：《中国医疗器械信息》2024年第3期116-118,共3页China Medical Device Information

摘　　要：目的:探讨肉眼血尿对尿常规检查的影响及处理方法,为临床提供参考。方法:将2022年6月~2023年6月本院诊治的100例血尿患者纳入观察研究中,均接受尿常规化验,取中段尿液样本,观察并分析离心处理前后的尿常规检查结果。结果:沉渣镜检白细胞阳性25例,阴性75例,以此为金标准,离心处理前肉眼血尿尿常规干化学法检测的假阳性率为93.33%,离心处理后为36.0%,相比差异存在统计学意义(P<0.05);肉眼血尿中,红细胞达20×10^(9)/L时,白细胞酯酶开始呈±,在50~200×10^(9)/L时呈+,100×10^(9)/L时,蛋白质呈+,酮体出现±;葡萄糖、亚硝酸盐、胆红素及尿胆原结果不受血尿浓度影响。离心处理可基本消除酮体假阳性,但无法消除蛋白质假阳性。结论:肉眼血尿会对尿常规检查结果产生影响,但通过离心处理基本可以消除,临床上应以显微镜检查结果为准。Objective:To explore the impact of gross hematuria on urine routine examination and its management methods,providing reference for clinical practice.Methods:100 patients with hematuria diagnosed and treated in our hospital from June 2022 to June 2023 were included in the observation study.All patients underwent routine urine tests,and mid stage urine samples were taken.The results of routine urine tests before and after centrifugation treatment were observed and analyzed.Results:There were 25 cases of positive and 75 cases of negative white blood cell esterase detected by sediment microscopy in this group.Using this as the gold standard,the false positive rate of naked eye blood,urine,routine dry chemistry test before centrifugation was 93.33%,and after centrifugation was 36.0%.The difference was statistically significant(P<0.05);In gross hematuria,when red blood cells reach 20×10^(9)/L,the white blood cell esterase begins to show ±,and at 50-200×10^(9)/L,it shows+.At 100×10^(9)/L,protein shows+,and ketone bodies appear±;The results of glucose,nitrite,bilirubin,and urinary bilirubin are not affected by the concentration of blood and urine.Centrifuge treatment can basically eliminate ketone body false positives,but cannot eliminate protein false positives.Conclusion:Macroscopic hematuria can have an impact on the results of routine urine examination,but it can be basically eliminated through centrifugation.In clinical practice,the results of microscopic examination should be used as the standard.

关 键 词：肉眼血尿 尿常规 假阳性 干化学分析 白细胞酯酶 

分 类 号：R446.1[医药卫生—诊断学]