基于“火与元气不两立”论化疗后不良反应  

Discussion On Post-chemotherapy Adverse Reactions based on the Theory of“Fire and Original Qi are Restricted”

作　　者：王子璇 姬佳琦 蒋士卿 WANG Zixuan;JI Jiaqi;JIANG Shiqing(Henan University of Traditional Chinese Medicine,Zhengzhou,450046;The First Affiliated Hospital of Henan University of Traditional Chinese Medicine)

机构地区：[1]河南中医药大学,河南省郑州市450046 [2]河南中医药大学第一附属医院

出　　处：《中医杂志》2024年第4期419-423,427,共6页Journal of Traditional Chinese Medicine

基　　金：河南省科技厅科技攻关计划(212102311125);河南省中医管理局河南省中医药科学研究专项课题(2019ZYZD06)。

摘　　要：化疗药物属于中医学“药毒”,其性峻猛,在杀伤肿瘤细胞的同时损伤人体元气,脾胃功能首先受损。基于李杲“火与元气不两立,一胜则一负”观点,认为火与元气的平衡是维持机体物质能量代谢的保障。元气作为人体生命活动的原动力,即为统领一身之气的“阳气”,脾胃功能受损,后天补充乏源,致使阳气不足,阴火亢盛,表现为化疗后机体的各种不良反应。以补益脾胃、升举阳气为治则,运用甘温除热的治法,可选用补中益气汤、当归补血汤等治疗化疗后机体出现的以火邪伤津耗气、阴虚火旺为主要证候特征的不良反应,缓解相关症状,既能保证化疗足量用药周期,同时还可以提高抗肿瘤疗效,提高患者生活质量。Traditional Chinese medicine holds that chemotherapy drugs belong to“medicinal toxins”,which are fierce in nature,and while killing tumor cells,they also damage human vitality,firstly disturbing spleen and stomach functions.Based on LI Gao's theory that“fire and original qi are restricted to each other,and one wins while the other loses”,it is believed that the balance between fire and original qi is the guarantee to maintain the material and energy metabolism of the body.As the driving force of human life activities,original qi is the“yang qi”that dominates the qi of the whole body.When the function of spleen and stomach is impaired,and the replenishment of acquired source is insufficient,there will be deficiency of yang qi and hyperactivity of yin fire,manifested as various adverse reactions of the body after chemotherapy.Following the treatment principle of tonifying the spleen and stomach and lifting yang qi,it is recommended to use sweet and warm medicinals to remove heat,and take formulas such as Buzhong Yiqi Decoc⁃tion(补中益气汤)and Danggui Buxue Decoction(当归补血汤)to treat various post-chemotherapy adverse reactions mainly manifested as fire pathogen damaging fluid and consuming qi,yin deficiency and fire exuberance,alleviate re⁃lated symptoms,which can not only ensure adequate chemotherapy cycle,but also improve the anti-tumor effect,and improve the quality of life of patients.

关 键 词：化疗 不良反应 火 元气 李杲 《脾胃论》 

分 类 号：R273[医药卫生—中西医结合]