鼓室硬化治疗的研究进展  

Advances in research on treatment of tympanosclerosis

作　　者：王新 梅凌云[1,2] 蒋璐 WANG Xin;MEI Lingyun;JIANG Lu(Department of Otolaryngology Head and Neck Surgery,Xiangya Hospital of Central South University,Changsha,410008,China;Hunan Province Key Laboratory of Otolaryngology Critical Diseases)

机构地区：[1]中南大学湘雅医院耳鼻咽喉头颈外科,长沙410008 [2]耳鼻咽喉重大疾病湖南省重点实验室

出　　处：《临床耳鼻咽喉头颈外科杂志》2024年第1期86-90,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：鼓室硬化是鼓膜固有层及中耳黏膜下层在长期慢性炎性刺激下发生的透明变性和钙质沉着。目前治疗主要依靠手术清除硬化灶及听骨链重建,但当清除累及面神经骨管、前庭窗龛等重要结构的硬化灶时,可能导致面瘫、眩晕及感音神经性耳聋等术后并发症。如何能更安全有效地治疗鼓室硬化成为国内外的研究目标。近年来在治疗手段上有一些新的探索,为此,本文对鼓室硬化治疗的最新研究进展进行综述。Tympanosclerosis is the hyaline degeneration and calcium deposition of the lamina propria of tympanic membrane and the submucosa of middle ear under long-term chronic inflammatory stimulation.At present,treatment primarily involves the surgical removal of sclerotic foci and reconstruction of auditory ossicular chain.However,excision of sclerotic lesions near critical structures like the facial nerve canal and vestibular window may result in complications like facial paralysis,vertigo,and sensorineural hearing loss.Developing safer and more effective treatments for tympanosclerosis has become an international research focus.Recent years have seen novel explorations in the treatment of tympanosclerosis.Therefore,this article reviews the latest advancements in research on the treatment of tympanosclerosis.

关 键 词：鼓室硬化 手术治疗 2-巯基乙磺酸钠 

分 类 号：R764.32[医药卫生—耳鼻咽喉科]