重构本草——苍耳子  

Reconstruction of Chinese materia medica-siberian cocklebur fruit

作　　者：翟天纲 谢伟楠 赵锡艳[1] ZHAI Tiangang;XIE Weinan;ZHAO Xiyan(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学,北京100029

出　　处：《长春中医药大学学报》2024年第3期255-258,共4页Journal of Changchun University of Chinese Medicine

基　　金：国家重点研发计划“中医药现代化”重点专项(2022YFC3502100);国家自然科学基金(82205089);中央级公益性科研院所基本科研业务费专项资金(ZZ13-YQ-030);中国中医科学院科技创新工程重大攻关项目(CI2021A01614);中国中医科学院广安门医院临床医学研究中心建设专项经费(2022LYJSZX13);中央高水平中医医院临床研究和成果转化能力提升项目—传承名老中医药专家学术经验专项(HLCMHPP2023009)。

摘　　要：通过古籍文献调研,梳理中医临床及中药学等学科领域内知名专家学者的认识及应用经验,结合中医药现代研究成果,归纳出苍耳子:功效主要为散风寒,通鼻窍,祛风湿。症靶为鼻塞流涕、皮肤瘙痒、头痛。现代药理研究发现苍耳子及其有效成分具有抗炎镇痛、抗过敏等作用。苍耳子有毒,成人中肝肾功能受损多见。经过高温炮制后,易于去刺,可降低毒性,保证用药安全。临床使用剂量为3~15 g,需严格控制用量,从小剂量开始,逐步增加至满意效果。同时,中病即止,不宜长期续服,以降低不良反应发生率。Through the investigation of ancient books and the sorting of the understanding and application experience of famous experts and scholars in the fields of traditional Chinese medicine clinical medicine and science of Chinese materia medica,combined with the modern research achievements of traditional Chinese medicine,it is cloncluded that siberian cocklebur fruit mainly has the effects of dispelling wind-cold,clearing nose orifices and dispeling wind and eliminating dampness.The symptom targets are nasal obstrtuction,snotty,pruritus,and headache.Modern pharmacology studies have found that siberian cocklebur fruit and its active ingredients have anti-inflammatory,analgesic and anti-allergic effects.Siberian cocklebur fruit is poisonous,and damage to liver and kidney functions is more common in adults.After high-temperature processing,it is easy to remove the thorns,which can reduce toxicity and ensure drug safety.The clinical dosage is 3-15 g,and the dosage needs to be strictly controlled.The dosage should start from a small dosage and gradually increase to a satisfactory effect.At the same time,the treatment should be stopped promptly when the disease receives appropriate treatment,because this herbal medicine is not suitable for long-term continuous use to reduce the incidence of adverse reactions.

关 键 词：苍耳子 症靶 重构本草 临床回归 

分 类 号：R281[医药卫生—中药学]