实时三维超声心动图及二维斑点追踪成像技术评估预激综合征患者左心室收缩同步性  

Applying real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging to evaluation of left ventricular systolic synchrony in patients with preexcitation syndrome

作　　者：宋焱 耿峰 王永[2] SONG Yan;GENG Feng;WANG Yong(Department of Cardiac Function,The Second People′s Hospital of Wuhu(Wuhu Hospital,East China Normal University),Wuhu 241000,Anhui,China)

机构地区：[1]华东师范大学附属芜湖医院芜湖市第二人民医院心功能科,安徽芜湖241000 [2]华东师范大学附属芜湖医院芜湖市第二人民医院心血管内科,安徽芜湖241000

出　　处：《皖南医学院学报》2024年第1期60-63,共4页Journal of Wannan Medical College

基　　金：芜湖市科技成果转化项目(2022cg26)。

摘　　要：目的:应用实时三维超声心动图(RT-3DE)及二维斑点追踪成像(2D-STI)技术评估预激综合征患者左心室收缩同步性临床应用价值。方法:选取芜湖市第二人民医院预激综合征患者35例为病例组,选取同期健康体检者35例为正常对照组。应用2D-STI计算左心室17节段圆周应变达峰时间标准差(Tcs-SD)、纵向应变达峰时间标准差(Tls-SD)、圆周应变率达峰时间标准差(Tcsr-SD)、纵向应变率达峰时间标准差(Tlsr-SD)参数水平值。应用RT-3DE记录左心室舒张末容积(LVEDV)、左心室收缩末容积(LVESV)、左心室射血分数(LVEF);分析17节段左心室容积-时间曲线(VTC),选取16节段最小收缩末容积时间差的标准差(Tmsv16-SD)、16节段最小收缩末容积时间差的最大时间差(Tmsv16-Dif)、校正后的16节段最小收缩末容积时间标准差(Tmsv16-SD%)、校正后的16节段最小收缩末容积时间最大时间差(Tmsv16-Dif%)进行同步记录分析。结果:①病例组Tcs-SD、Tls-SD、Tcsr-SD、Tlsr-SD均高于对照组(P<0.001)。②病例组LVEDV、LVESV均高于对照组(P<0.001),而两组间LVEF差异无统计学意义(P>0.05)。③病例组Tmsv16-SD、Tmsv16-Dif、Tmsv16-SD%、Tmsv16-Dif%水平均高于对照组(P<0.001)。结论:预激综合征患者左心室心肌存在收缩不同步运动,RT-3DE及2D-STI能够对预激综合征患者的左心室收缩功能进行量化,并且能够对其左心室收缩同步性进行有效评估。Objective:To investigate the value of real-time three-dimensional echocardiography(RT-3DE)and two-dimensional speckle tracking imaging(2D-STI)applied to evaluating left ventricular systolic synchrony in patients with preexcitation syndrome.Methods:Thirty-five patients with preexcitation syndrome were included in case group,and another 35 healthy subjects undergoing physical examination in our hospital at the corresponding period were recruited in control group.2D-STI was used to measure the following parameters in 17 left ventricle(LV)segments,including the standard deviations of time to peak circumferential strain(Tcs-SD),longitudinal strain(Tls-SD),circumferential strain rate(Tcsr-SD)and longitudinal strain rate(Tlsr-SD).RT-3DE was used to synchronously record and analyze left ventricular end-diastolic volume(LVEDV),end-systolic volume(LVESV),ejection fraction(LVEF),volume-time curve(VTC)of the 17 segments,standard deviation(Tmsv16-SD)and maximum difference(Tmsv16-Dif)of the time to minimum systolic volume of the 16 LV segments,and those after correction(Tmsv16-SD%and Tmsv16-Dif%).Results:①The indicators,including Tcs-SD,Tls-SD,Tcsr-SD and Tlsr-SD,were higher in case group than in control group(P<0.001);②LVEDV and LVESV were higher in case group than in control group(P<0.001),yet the LVEF level remained no difference between groups(P>0.05);③Patients in the case group had higher levels of Tmsv16-SD,Tmsv16-Dif,Tmsv16-SD%and Tmsv16-Dif%than those in the control group(P<0.001).Conclusion:Left ventricular systolic asynchrony presents in patients with preexcitation syndrome.RT-3DE and 2D-STI can be used to quantify left ventricular systolic function in patients with preexcitation syndrome and effectively evaluate left ventricular systolic synchrony.

关 键 词：预激综合征 左心室收缩同步性 实时三维超声心动图 二维斑点追踪成像技术 

分 类 号：R540.45[医药卫生—心血管疾病] R541[医药卫生—内科学]