抗敏通窍方联合氦氖激光治疗对儿童过敏性鼻炎的疗效观察  

Curative effect of Kangmin Tongqiao decoction combined with Helium-Neon laser treatment on allergic rhinitis in children

作　　者：杨楚文 赵鋆[1] 崔晨[1] 宋勤丽 芦小叶 周芳源 YANG Chuwen;ZHAO Jun;CUI Chen;SONG Qinli;LU Xiaoye;ZHOU Fangyuan(Pediatrics of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院儿科,上海201203 [2]上海中医药大学

出　　处：《中国中西医结合儿科学》2024年第1期66-71,共6页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：上海市进一步加快中医药传承创新发展三年行动计划(ZY[2021-2023]-0206-02);上海市卫生健康委员会科研项目(20214Y0380)。

摘　　要：目的 抗敏通窍方联合氦氖激光对过敏性鼻炎患儿的临床疗效验证。方法 选取2022年1月至2023年1月我院儿科门诊就诊的3~14岁肺气虚寒型变应性鼻炎患儿104例,随机分为观察组和对照组各52例。两者均常规运用生理海水冲洗鼻腔作为基础治疗,观察组予以抗敏通窍方联合氦氖激光治疗,对照组予以氦氖激光治疗。治疗2周,观察两组临床疗效、临床症状评分、外周血嗜酸性粒细胞计数绝对值、嗜酸性粒细胞百分比、血清总IgE水平,并比较两组患儿鼻结膜炎生活质量问卷评分、睡眠质量、焦虑状态改善情况。结果 观察组与对照组总有效率分别为100.0%(52/52)、61.54%(32/52),差异有统计学意义(P<0.05)。治疗后两组临床症状评分、外周血嗜酸性粒细胞计数、血嗜酸性粒细胞百分比、血总IgE、鼻结膜炎生活质量问卷评分、匹兹堡睡眠质量指数、焦虑评分均明显低于治疗前,且观察组临床症状评分、外周血嗜酸性粒细胞计数、血嗜酸性粒细胞百分比、鼻结膜炎生活质量问卷评分、焦虑评分均显著低于对照组,差异有统计学意义(P<0.05)。结论 抗敏通窍方联合氦氖激光治疗对儿童过敏性鼻炎疗效显著,可明显改善患儿生活质量、睡眠质量以及焦虑状态。Objective To verify the clinical efficacy of Kangmin Tongqiao decoction combined with Helium-Neon laser in children with allergic rhinitis.Methods Totally 104 children aged 3 to 14 years meeting the diagnostic criteria for allergic rhinitis treated in our hospital from Jan.2022 to Jan.2023 were randomly divided into treatment group and control group,with 52 children in each group.Both of them routinely use physiological seawater to flush the nasal cavity as the basic treatment.The treatment group was treated with Kangmin Tongqiao decoction combined with Helium-Neon laser,and the control group was treated with Helium-Neon laser.After 2 weeks of treatment,the clinical efficacy,clinical symptom score,absolute value of peripheral blood eosinophil count,percentage of eosinophils and total serum IgE level were observed,and the improvement in score of life quality questionnaire,sleep quality and anxiety status were compared between the two groups.Results The total response rate of the treatment and control groups was 100.0%(52/52) and 61.54%(32/52),respectively,the difference being statistically significant(P<0.05).After treatment,the clinical symptom score,peripheral blood eosinophil count,blood eosinophil percentage,total IgE,score of life quality questionnaire,sleep quality score,and anxiety score were significantly lower,while the clinical symptom score,peripheral blood eosinophil count,blood eosinophil percentage,score of life quality questionnaire,and anxiety score of treatment group were significantly lower than those of the control group(P<0.05).Conclusion Kangmin Tongqiao decoction combined with Helium-Neon laser has significant effect on allergic rhinitis,which can significantly improve the quality of life,sleep quality and anxiety in children.

关 键 词：过敏性鼻炎 抗敏通窍方 氦氖激光 临床疗效 儿童 

分 类 号：R725.6[医药卫生—儿科]