肠内免疫微生态营养支持应用于重症急性胰腺炎患者的效果分析  

Effect of enteral immune microecological nutrition support in treatment of severe acute pancreatitis

作　　者：苏玉敏[1] 白亚楠 Su Yumin;Bai Yanan(Department of Emergency Intensive Care Unit,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院急诊重症监护病区,郑州450000

出　　处：《中国实用医刊》2023年第22期62-65,共4页Chinese Journal of Practical Medicine

摘　　要：目的分析肠内免疫微生态营养支持在重症急性胰腺炎患者治疗中的应用效果。方法抽取郑州大学第一附属医院2022年3月至2023年3月收治的80例重症急性胰腺炎患者作为研究对象,按随机数字表法分为对照组和观察组,每组40例。对照组予以肠内营养支持,观察组予以肠内免疫微生态营养支持。比较两组的治疗效果、肠道菌群数量及胃肠功能恢复水平。结果治疗后,观察组的总有效率(37/40,92.50%)高于对照组(30/40,75.00%),P<0.05;观察组患者的肠杆菌、肠球菌数量均少于对照组,而乳杆菌与双歧杆菌数量则多于对照组(P<0.05);观察组患者的腹痛腹胀消失时间、经口进食时间、血淀粉酶恢复时间、排便排气恢复时间、肠鸣音恢复时间及住院时间均短于对照组(P均<0.05)。结论重症急性胰腺炎患者临床治疗中采取肠内免疫微生态营养支持可取得较好效果,不仅能提高临床疗效,还能调整肠道菌群,促进胃肠功能恢复。Objective To analyze the effect of enteral immune microecological nutrition support in the clinical treatment of patients with severe acute pancreatitis.Methods Eighty patients with severe acute pancreatitis admitted to the First Affiliated Hospital of Zhengzhou University from March 2022 to March 2023 were selected as the research objects,and they were divided into control group and observation group by random number table method,with 40 cases in each group.The control group was given enteral nutrition support,and the observation group was given enteral immune microecological nutrition support.The therapeutic effect,the number of gut microbiota and the recovery of gastrointestinal function of the two groups were compared.Results After treatment,the total effective rate of the observation group(37/40,92.50%)was higher than that of the control group(30/40,75.00%),P<0.05.The number of enterobacter and enterococcus in the observation group were lower than those in the control group,while the number of lactobacillus and bifidobacterium were higher than those in the control group(P<0.05).The disappearance time of abdominal pain and distension,oral feeding time,blood amylase recovery time,defecation and exhaust recovery time,bowel sound recovery time and hospital stay in the observation group were shorter than those in the control group(all P<0.05).Conclusions In the clinical treatment of patients with severe acute pancreatitis,enteral immune microecological nutrition support can achieve remarkable results,which can improve the clinical efficacy,regulate gut microbiota and promote the recovery of gastrointestinal function.

关 键 词：胰腺炎 肠内免疫微生态营养支持 肠内营养支持 肠道菌群 胃肠功能 

分 类 号：R657.51[医药卫生—外科学]