双重血浆分子吸附联合血浆置换治疗肝移植围手术期肝衰竭患儿3例  

Applications of dual plasma molecular adsorption plus plasmapheresis for liver failure during perioperative period of liver transplantation in children:a report of 3 cases

作　　者：孙雁[1] 王兵[1] 高思楠[1] 于立新[1] 刘懿禾[1] Sun Yan;Wang Bing;Gao Sinan;Yu Lixin;Liu Yihe(Surgical Intensive Care Unit,First Central Municipal Hospital,Key Municipal Laboratory of Organ Transplantation,Tianjin 300380,China)

机构地区：[1]天津市第一中心医院外科重症监护室,天津市器官移植重点实验室,天津300380

出　　处：《中华器官移植杂志》2023年第12期750-753,共4页Chinese Journal of Organ Transplantation

基　　金：北京肝胆相照公益基金会人工肝专项基金(iGandanF-1082022-RGG029)。

摘　　要：肝衰竭是一种进展迅速的临床危重症,死亡率极高。人工肝治疗是救治肝衰竭的重要方法。但是对于儿童肝衰竭患者,特别是婴幼儿,由于缺乏与体重匹配的血液净化耗材,可选择的人工肝治疗方式有限。近年来,天津市第一中心医院应用双重血浆分子吸附联合血浆置换救治肝移植围手术期的肝衰竭儿童,治疗过程顺利,清除毒素的效果满意,现进行总结及经验分享。Liver failure(LF)is a rapidly progressing critical illness with a high mortality rate in clinical practices.Artificial liver therapy has been a major cure for LF.However,for LF infants and toddlers,therapeutic options for artificial liver have remained limited due to a great lack of weight-matched blood purification supplies.In recent years,our center has applied double plasma molecular adsorption plus plasmapheresis for managing LF children during perioperative period of liver transplantation.Treatment is smooth with an excellent efficacy of removing toxins.Here our institutional experiences were summarzied.

关 键 词：儿童 婴儿 肝衰竭 血浆置换 

分 类 号：R726.5[医药卫生—儿科]