Biograph Vision 600 PET性能测试与分析  

Biograph Vision 600 PET performance testing and analysis

作　　者：李红磊[1] 王群 杨森 刘杰[1] LI Honglei;WANG Qun;YANG Sen;LIU Jie(Department of Nuclear Medicine,China-Japan Friendship Hospital,Beijing 100029 China;Department of radiology,Guang'anmen Hospital,Beijing 100053 China)

机构地区：[1]中日友好医院核医学科,北京100029 [2]广安门医院放射科,北京100053

出　　处：《中国辐射卫生》2023年第6期668-672,678,共6页Chinese Journal of Radiological Health

摘　　要：目的 依据NEMA NU2—2012标准对Biograph Vision 600 PET/CT进行性能检测及研究,以实现可靠、可重复和系统间可比较的性能测量,为以后的设备稳定性检测及状态检测提供依据。方法 Biograph Vision PET设备采用基于硅光电倍增管的探测器,具有3.2 mm的硅酸镥晶体,并全面覆盖闪烁体区域。参照NEMA NU2—2012标准的测试模型和方法对Biograph Vision PET的空间分辨率、灵敏度、等效噪声计数率、散射分数、符合计数率、图像质量、散射校正和飞行时间分辨率等性能参数进行测试。结果 Biograph Vision 600 PET视野中心1 cm处横向和轴向空间分辨率分别为3.69 mm和3.81 mm,10 cm处横向和轴向空间分辨率分别为4.29 mm和4.48 mm,灵敏度为17.5 kcps/MBq,随着计数率增加到峰值噪声等效计数率,飞行时间分辨率从210 ps变化到215 ps。在30.3 kBq/mL时NEMA峰值噪声等效计数率为247 kcps。对应的散射分数为34.8%。使用NEMA模体得到的整体图像质量对比度范围为73.6%~92.8%,背景变异系数范围为2.3%~6.5%;平均肺插件残余误差为3.4%;飞行时间分辨率为210 ps。结论 本性能检测根据NEMA NU2—2012标准完成,各项参数均优于出厂标准,为其他单位在设备选择时提供参考,为以后的设备稳定性检测及状态检测提供依据。Objective To test and analyze the performance of Biograph Vision 600 PET/CT according to the NEMA NU2—2012 standard to achieve reliable,repeatable,and inter-system comparable performance measurement,and to provide a basis for future equipment stability testing and status detection.Methods The Biograph Vision PET equipment features a detector based on silicon photomultipliers,with 3.2 mm lutetium oxyorthosilicate crystals and full cover of the scintillation region.The spatial resolution,sensitivity,noise-equivalent count rate,scatter fraction,coincidence count rate,image quality,scatter correction,and time-of-flight resolution of Biograph Vision PET were tested by referring to the test model and method of the NEMA NU2—2012 standard.Results The Biograph Vision 600 PET equipment showed lateral and axial spatial resolutions of 3.69 mm and 3.81 mm at 1 cm off-center of the field of view,respectively and of 4.29 mm and 4.48 mm at 10 cm,respectively.The sensitivity was 17.5 kcps/MBq.The time-of-flight resolution changed from 210 ps to 215 ps as the count rate increased to the peak noise equivalent count rate.The NEMA peak noise-equivalent count rate was 247 kcps at 30.3 kBq/ml.The corresponding scatter fraction was 34.8%.With the NEMA module,the overall image quality contrast range was 73.6%-92.8%,and the background variability was 2.3%-6.5%;the mean lung residual error was 3.4%;and the time-of-flight resolution was 210 ps.Conclusion This performance test was performed according to the NEMA NU2—2012 standard,showing that all parameters were better than the ex-factory standard,which can provide a reference for other institutions selecting equipment and also provide a basis for future equipment stability testing and status detection.

关 键 词：正电子发射型计算机断层显像 NEMA 性能检测 质量控制 飞行时间 

分 类 号：R445.5[医药卫生—影像医学与核医学]