可吸收手术缝合线研究进展  

Research progress in absorbable surgical sutures

作　　者：杨智超 刘淑强 吴改红 贾潞 张曼 李甫 李慧敏 YANG Zhichao;LIU Shuqiang;WU Gaihong;JIA Lu;ZHANG Man;LI Fu;LI Huimin(College of Textile Engineering,Taiyuan University of Technology,Taiyuan,Shanxi 030024,China)

机构地区：[1]太原理工大学轻纺工程学院,山西太原030024

出　　处：《纺织学报》2024年第1期230-239,共10页Journal of Textile Research

基　　金：山西省基础研究计划项目(20210302123114,202203021211146);山西省科技成果转化引导专项项目(202104021301053);山西省社科联2021年度重点课题(SSKLZDKT2021025);山西省高等学校大学生创新创业训练计划项目(20220125);山西省基础研究计划(青年)(20210302124684)。

摘　　要：可吸收手术缝合线是当今国际生物医用纺织领域的研究热点之一。为了掌握可吸收手术缝合线的创新方向以及临床和产业化需求提升我国可吸收手术缝合线的自主知识产权;首先介绍了可吸收缝合线的发展历程以及性能要求;其次列举了羊肠线、胶原线、甲壳质和海藻酸盐4种天然材料在天然可吸收缝合线方面的应用并总结分析最新国内外相关研究;然后综述了聚乳酸、聚乙醇酸、聚己内酯和聚乙烯醇4类合成高分子材料在可吸收缝合线方面的应用并总结分析国内外最新相关研究;系统对比了各种制备原料开发可吸收手术缝合线的优缺点,并侧重分析了可吸收手术缝合线的力学性能、降解性能以及附加抗菌性能3个重要指标。分析认为:目前市面上的可吸收手术缝合线仍以国外进口为主导,我国对于可吸收手术缝合线的开发仍处于实验室阶段,较少能够投入市场以及临床应用,另外,对用天然材料开发的可吸收手术缝合线研究甚少。同时,提出各类材料作为可吸收手术缝合线的优缺点,为新型可吸收手术缝合线的开发提供参考。Significance Biomedical textiles are one of the most innovative and technologically advanced research fields in the textile industry today.Surgical sutures are one of the most used medical devices in clinical surgery,and research and development of sutures have been active worldwide.As a new generation of surgical sutures,absorbable surgical sutures are the″darling″of the medical community,with extremely important applications in obstetrics and gynecology,surgery,otolaryngology,ophthalmology,dentistry,and so on.Absorbable surgical sutures have become the first choice of surgeons in surgical procedures by virtue of their self-degrading,non-removable and less painful properties,and patients using absorbable surgical sutures are benefitted from having minimal visible scarring on the skin after healing,enhancing patient satisfaction.Although the development of absorbable surgical sutures is now at a relatively mature stage,many high value-added absorbable surgical sutures with excellent functionality are still in the laboratory stage and cannot be industrially produced and marketed for clinical applications.Therefore,this paper focuses on the analysis of various raw materials for preparation of absorbable surgical sutures based on the latest relevant research literature to systematically summarize the current research status of absorbable surgical sutures,promote the innovative development of absorbable surgical sutures and enhance the industrial production of absorbable surgical sutures.Progress The development of absorbable sutures and their performance requirements,the history of the development of absorbable surgical sutures from ancient times to the present day are introduced first.The development of the raw materials for their preparation from single to diversified are elaborated.The specific development history is shown,and the mainstream productson the market today are shown.In addition,the properties of absorbable surgical sutures,such as good biocompatibility and good knot strength,as well as the smooth

关 键 词：生物医用纺织品 可吸收手术缝合线 天然材料 合成高分子材料 降解性能 抗菌性能 

分 类 号：TS102.5[轻工技术与工程—纺织工程]