中医药治疗难治性心绞痛的临床研究进展  

Clinical research progress on the treatment of refractory angina pectoris with traditional Chinese medicine

作　　者：毛竹青 曹小勇 MAO Zhuqing;CAO Xiaoyong(Department of Special Service,Joint Logistic Support Force 988th Hospital,Henan Province,Zhengzhou450042,China)

机构地区：[1]联勤保障部队第九八八医院特勤科,河南郑州450042

出　　处：《中国当代医药》2024年第6期180-183,共4页China Modern Medicine

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20220917)。

摘　　要：难治性心绞痛(RFA)即经过常规药物治疗及手术治疗后,仍持续3个月以上反复发作的一种心绞痛。RFA作为临床最严重且难治的心绞痛类型,其发病率在不断增加,是目前心血管研究领域关注的重点。RFA的病因病机的实质为本虚标实,以心阳不足为病之本,气滞、血瘀、痰浊、寒凝为病之标。中医证候以气虚、血瘀、痰浊为主,主要证型有气虚血瘀、气滞血瘀、痰阻血瘀、寒凝心脉、气阴两虚、阳虚水泛及心阳欲脱7种。中医治疗以口服汤药、中成药为主,西医治疗包括β受体阻滞剂、硝酸酯类、阿司匹林等药物治疗以及增强型体外反搏治疗、脊髓刺激术、心脏体外震波等体外治疗。根据现代医学研究进展,归纳出较为常用的西药治疗、中药治疗、中成药治疗及体外特色治疗方法,为RFA的进一步研究提供理论支持。Refractory angina pectoris(RFA)is a type of angina that persists for more than three months after routine medication and surgical treatment.As the most serious and refractory type of angina pectoris in clinic,the incidence rate of RFA is increasing,which is the focus of cardiovascular research at present.The essence of the etiology and pathogenesis of RFA is based on deficiency and excess,with deficiency of heart yang as the foundation of the disease,and qi stagnation,blood stasis,phlegm turbidity,and cold coagulation as the criteria of the disease.The main syndromes of traditional Chinese medicine are qi deficiency,blood stasis,and phlegm turbidity.The main types of syndromes include qi deficiency and blood stasis,qi stagnation and blood stasis,phlegm obstruction and blood stasis,cold coagulation of heart meridians,qi yin deficiency,yang deficiency and water flooding,and the desire to lose heart yang.Traditional Chinese medicine treatment is mainly oral decoction and traditional Chinese patent medicines and simple preparations,while western medicine treatment includesβReceptor blockers,nitrates,aspirin and other drugs for treatment,as well as enhanced extracorporeal counterpulsation therapy,spinal cord stimulation surgery,extracorporeal cardiac shock wave therapy,and other extracorporeal therapies.According to the progress of modern medical research,the commonly used western medicine treatment,traditional Chinese medicine treatment,traditional Chinese patent medicines and simple preparations treatment and in vitro characteristic treatment methods are summarized to provide theoretical support for further research of RFA.

关 键 词：难治性心绞痛 研究进展 胸痹心痛 病因病机 

分 类 号：R541.4[医药卫生—心血管疾病]