多囊卵巢综合征患者孕早期自然流产的危险因素分析  

Risk factors of spontaneous abortion in the first trimester of polycystic ovary syndrome

作　　者：叶敏欢[1,2] 李淑芳 郑晓宇[1,2] 郑楚丽 欧湘红 Ye Minhuan;Li Shufang;Zheng Xiaoyu;Zheng Chuli;Ou Xianghong(Department of Gynecology,Dongguan Houjie Hospital,Dongguan 523000,China;Reproductive Medicine Center,The Second People's Hospital of Guangdong Province/Guangdong Medical University,Guangzhou 510006,China)

机构地区：[1]东莞市厚街医院妇科,广东东莞523000 [2]广东医科大学/广东省第二人民医院生殖医学中心,广东广州510006

出　　处：《实用妇科内分泌电子杂志》2023年第33期48-50,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨多囊卵巢综合征(PCOS)患者孕早期自然流产的危险因素,为临床防治提供有利参考借鉴。方法回顾性分析60例PCOS患者的临床资料。根据患者是否存在早期自然流产情况分为流产组(24例)与未流产组(36例)。收集患者的一般资料、既往病史、实验室指标,经单因素与多因素Logistic回归分析PCOS患者孕早期自然流产的危险因素。结果两组月经紊乱史、流产史、家族史、高雄体征、睾酮(T)及胰岛素抵抗指数(HOMA-IR)指标比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析显示:流产史、家族史、高雄体征、T、HOMA-IR均是影响PCOS患者发生孕早期自然流产的独立危险因素(P<0.05)。结论临床应具体分析PCOS患者孕早期自然流产危险因素,指导针对性干预以改善患者预后。Objective To explore the risk factors of spontaneous abortion in the first trimester in patients with polycystic ovary syndrome(PcoS),and to provide beneficial reference for clinical prevention and treatment.Methods The clinical data of 60 patients with PcoS were analyzed retrospectively.According to whether the patients had early spontaneous abortion,they were divided into abortion group(24 cases)and non-abortion group(36 cases).The risk factors of spontaneous abortion in the first trimester of PCOS patients were analyzed by univariate and multivariate Logistic regression.Results There were statistically significant differences in menstrual disorder history,abortion history,family history,kaohsiung signs,testosterone(T)and insulin resistance Homeostasis Model Assessment index(HOMA-IR)between the two groups(P<0.05).Multivariate Logistic regression analysis showed that abortion history,family history,Kaohsiung signs,T and HOMA-IR were independent risk factors for spontaneous abortion in the first trimester of PCoS patients(P<0.05).Conclusion The risk factors of spontaneous abortion in the first trimester of PcoS patients should be analyzed and targeted intervention should be directed to improve the prognosis of patients.

关 键 词：多囊卵巢综合征 孕早期 自然流产 危险因素 

分 类 号：R714.21[医药卫生—妇产科学] R711.75[医药卫生—临床医学]