血清AFU、孕酮、β-HCG联合检验对诊断先兆流产的临床价值  

Clinical value of serum AFU,progesterone andβ-HCG combined test in the diagnosis of threatened abortion

作　　者：杨道贵 梁满超 陈秀英 Yang Daogui;Liang Manchao;Chen Xiuying(Department of Clinical Laboratory,Dongguan Marina Bay Central Hospital,Dongguan 523000,China)

机构地区：[1]东莞市滨海湾中心医院检验科,广东东莞523000

出　　处：《实用妇科内分泌电子杂志》2023年第33期109-111,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨血清α-L-岩藻糖苷酶(AFU)、孕酮、β-人绒毛膜促性腺激素(β-HCG)联合检验对诊断先兆流产的临床价值。方法选取120例先兆流产孕妇,根据其妊娠结局不同分为观察1组(继续妊娠)与观察2组(妊娠失败),各60例;另选取60例孕检健康孕妇作为对照组。检测三组孕妇血清AFU、孕酮、β-HCG水平,并比较不同检测结果的诊断效能。结果观察1组、观察2组血清AFU、孕酮、β-HCG水平均比对照组低(P<0.05),观察2组血清AFU、孕酮、β-HCG水平均比观察1组低(P<0.05)。联合AFU、孕酮及β-HCG水平诊断先兆流产的敏感度、准确率、特异度分别为86.67%、93.33%及90.00%,联合检测敏感度、准确率、特异度均高于单一水平检测(P<0.05)。结论先兆流产孕妇血清AFU、孕酮及β-HCG水平明显更低,联合检测可提高先兆流产疾病诊断准确率,为后续治疗提供重要的参考价值。Objective To investigate the clinical value of serum a-L-fucosidase(AFU),progesterone andβ-HCG combined test in the diagnosis of threatened abortion.Methods 120 pregnant women with threatened abortion were selected and divided into observation group 1(continued pregnancy)and observation group 2(pregnancy failure)according to their different pregnancy outcomes,with 60 cases each.Another 60 healthy pregnant women were selected as control group.Serum levels of AFU,progesterone andβ-HCG were detected in three groups of pregnant women,and the diagnostic efficacy of different detection results was compared.Results Serum AFU,progesterone andβ-HCG levels in observation group 1 and observation group 2 were lower than those in control group(P<0.05),and serum AFU,progesterone andβ-HCG levels in observation group 2 were lower than those in observation group 1(P<0.05).The sensitivity,accuracy and specificity of combined AFU,progesterone andβ-HCG levels in the diagnosis of threatened abortion were 86.67%,93.33%and 90.00%,respectively.The sensitivity,accuracy and specificity of combined detection were higher than those of single level detection(P<0.05).Conclusion Serum levels of AFU,progesterone andβ-HCG in pregnant women with threatened abortion are significantly lower.Combined detection can improve the diagnostic accuracy of threatened abortion disease and provide important reference value for follow-up treatment.

关 键 词：先兆流产 妊娠结局 诊断价值 

分 类 号：R714.21[医药卫生—妇产科学]