有氧联合抗阻运动对中老年2型糖尿病患者糖脂代谢影响的meta分析  

Effects of aerobic combined resistance exercise on glucose and lipid metabolism in middle-aged and elderly patients with type 2 diabetes:A meta-analysis

作　　者：胡才玉 李军文[2] 王红彦 HU Caiyu;LI Junwen;WANG Hongyan(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan 610075,China;Department of Nursing,Chengdu First People′s Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]成都中医药大学护理学院,四川成都610075 [2]成都市第一人民医院护理部,四川成都610041

出　　处：《现代医药卫生》2024年第5期823-827,共5页Journal of Modern Medicine & Health

摘　　要：目的 探讨有氧运动(AT)联合抗阻运动(ART)对中老年2型糖尿病患者糖脂代谢等指标的影响。方法 以“Type 2 diabetes、concurren、exercise、resistance、combine”等为关键词,检索Web of science、PubMed、Embase数据库,以“有氧联合抗阻运动、2型糖尿病、糖脂代谢”等为关键词检索中国知网、中国生物医学文献数据库、维普、万方数据库,检索时限从建库至2023年2月。将研究资料进行全面收集与整理,运用Cochrane偏倚风险评估工具对纳入文献进行方法学质量评价,采用RevMan5.4.0软件对数据进行统计学分析与处理。结果 共纳入研究文献10篇,其中中文文献8篇,外文文献2篇。受试者共669例,其中试验组357例(以AT联合ART为主要干预手段),对照组342例(以AT运动或常规护理为主)。meta分析结果显示,试验组患者空腹血糖[均方差(MD)=-1.33,95%可信区间(95%CI)-1.62~-1.04,I^(2)=35%,P<0.01]、糖化血红蛋白(MD=-1.43,95%CI-1.60~-1.27,I^(2)=38%,P<0.01)、低密度脂蛋白(MD=-0.51,95%CI-0.58~-0.44,I^(2)=20%,P<0.01)、甘油三酯(MD=-0.60,95%CI-1.07~-0.13,I^(2)=92%,P=0.01)、总胆固醇(MD=-1.19,95%CI-1.35~-1.02,I^(2)=0,P<0.01)均优于对照组,差异均有统计学意义。2组患者高密度脂蛋白(MD=0.06,95%CI-0.04~0.16,I^(2)=0,P=0.23)比较,差异无统计学意义。结论 AT联合ART改善中老年2型糖尿病患者糖脂代谢紊乱的效果优于单纯AT。Objective To investigate the effects of aerobic exercise(AT)combined with aerobic resistance exercise(ART)on glucose and lipid metabolism in middle-aged and elderly patients with type 2 diabetes.Methods′Type 2 diabetes,concurren,exercise,resistance,combine′were used as keywords to search Web of science,PubMed,and Embase databases.′Aerobic combined resistance exercise,type 2 diabetes,glucose and lipid metabolism′were used as keywords to search CNKI,CBM,VIP,and Wanfang databases.The retrieval time limit is from the establishment of the database to February 2023.The research data were collected and collated comprehensively.The Cochrane bias risk assessment tool was used to evaluate the methodological quality of the included literature,and RevMan5.4.0 software was used for statistical analysis and processing of the data.Results A total of 10 literatures were included,including eight Chinese literatures and two foreign literatures.A total of 669 subjects were enrolled,including 357 in the experimental group(AT combined with ART as the main intervention)and 342 in the control group(AT exercise or routine nursing).The results of meta analysis showed that fasting blood glucose[mean difference(MD)=-1.33,95%confidence interval(95%CI)-1.62--1.04,I^(2)=35%,P<0.01],glycosylated hemoglobin(MD=-1.43,95%CI-1.60--1.27,I^(2)=38%,P<0.01),low density lipoprotein(MD=-0.51,95%CI-0.58--0.44,I^(2)=20%,P<0.01),triglyceride(MD=-0.60,95%CI-1.07--0.13,I^(2)=92%,P=0.01),total cholesterol(MD=-1.19,95%CI-1.35--1.02,I^(2)=0%,P<0.01),in the experimental group were better than those in the control group.The differences were statistically significant.There was no significant difference in high-density lipoprotein between the two groups(MD=0.06,95%CI-0.04--0.16,I^(2)=0,P=0.23).Conclusion The effect of AT combined with ART on improving glucose and lipid metabolism disorder in middle-aged and elderly patients with type 2 diabetes is better than that of AT alone.

关 键 词：有氧联合抗阻运动 2型糖尿病 糖脂代谢 META分析 

分 类 号：R587.1[医药卫生—内分泌] R473.5[医药卫生—内科学]