上林县输入性间日疟和卵形疟与G6PD缺乏患者流行病学调查研究  

Epidemiological investigation of imported vivax malaria,ovale malaria and G6PD deficiency patients in Shanglin County

作　　者：覃宇城 潘茂华 李海连 温秀峰 周金花 林康明[2] 李利红 杨照青 黄亚铭 QIN Yucheng;PAN Maohua;LI Hailian;WEN Xiufeng;Zhou Jinhua;LIN Kangming;LI Lihong;YANG Zhaoqing;HUANG Yaming(Department of Infectious Diseases,the People′s Hospital of Shanglin/National Tropical Disease Research Center-Clinical Research Alliance of Infectious Diseases such as Parasitic Diseases in Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Nanning,Guangxi 530500,China;Department of Protozoa,Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention,Nanning,Guangxi 530028,China;College of Basic Medical,Kunming Medical University,Kunming,Yunnan 650500,China)

机构地区：[1]上林县人民医院感染性疾病科/国家热带病研究中心-上海交通大学医学院附属瑞金医院寄生虫病等感染性疾病临床研究联盟,广西南宁530500 [2]广西壮族自治区疾病预防控制中心原虫病科,广西南宁530028 [3]昆明医科大学基础医学院,云南昆明650500

出　　处：《现代医药卫生》2024年第5期828-831,共4页Journal of Modern Medicine & Health

基　　金：国家自然科学基金项目(U1802286,31860604);广西壮族自治区卫健委科研项目(Z-A20231282,Z-A20221274,Z20190892)。

摘　　要：目的统计分析上林县输入性间日疟和卵形疟与葡萄糖-6-磷酸脱氢酶(G6PD)缺乏患者流行病学特征,为疟疾防治提供科学依据。方法收集上林县人民医院2017年6月18日至2023年3月29日入院治疗输入性疟疾患者的数据进行整理分析。结果收治输入性疟疾患者共578例,其中恶性疟患者占40.48%(234/578),需要伯氨喹进行根治的间日疟、卵形疟及混合感染患者占37.54%(217/578);其中G6PD缺乏患者占10.90%(63/578),需根治的G6PD缺乏患者占9.68%(21/217)。结论上林县需要根治的输入性间日疟和卵形疟患者较多,特别是对G6PD缺乏又需根治的患者应加强管理,预防二代病例的出现。Objective To analyze the epidemiological characteristics of imported vivax malaria,ovale malaria and glucose-6-phosphate dehydrogenase(G6PD)deficiency in Shanglin County,and to provide a scientific basis for malaria prevention and control.Methods The data of patients with imported malaria admitted to the People′s Hospital of Shanglin from June 18,2017 to March 29,2023 were collected and analyzed.Results A total of 578 patients with imported malaria were admitted,of which 40.48%(234/578)were falciparum malaria patients,and 37.54%(217/578)were vivax malaria,oval malaria and mixed infection patients who needed primaquine for radical treatment.Among them,G6PD deficiency patients accounted for 10.90%(63/578),and G6PD deficiency patients requiring radical treatment accounted for 9.68%(21/217).Conclusion There are more patients with imported vivax malaria and ovale malaria who need to be cured in Shanglin County,especially for patients with G6PD deficiency who need to be cured,management should be strengthened to prevent the occurrence of second-generation cases.

关 键 词：输入性疟疾 间日疟 卵形疟 G6PD缺乏 根除治疗 流行病学调查 

分 类 号：R183[医药卫生—流行病学]