难治性SHPT患者行tPTX+AT术后复发的研究进展  

Research progress on recurrence after total parathyroidectomy combined with autologous transplantation surgery in patients with refractory secondary hyperparathyroidism

作　　者：卢东军(综述) 刘天奇(审校) LU Dongjun;LIU Tianqi(Youjiang College of Ethnic Medicine,Baise,Guangxi 533000,China;People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530021,China;Department of General Surgery,Jiangbin Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530021,China)

机构地区：[1]右江民族医学院,广西百色533000 [2]广西壮族自治区人民医院,广西南宁530021 [3]广西壮族自治区江滨医院普通外科,广西南宁530021

出　　处：《现代医药卫生》2024年第5期845-848,853,共5页Journal of Modern Medicine & Health

基　　金：广西壮族自治区卫健委医疗卫生适宜技术开发与推广应用项目(S2017083)。

摘　　要：继发性甲状旁腺功能亢进症(SHPT)是尿毒症患者进行长时间血液透析治疗过程中较为常见的并发症之一,SHPT患者经长时间的透析治疗最终发展为难治性SHPT,此时内科治疗效果较差甚至无效,手术治疗可使患者症状得到快速改善。目前,甲状旁腺全切除术联合自体移植术(tPTX+AT)是难治性SHPT患者主要的手术方式之一。然而近年来难治性SHPT患者行tPTX+AT后的康复管理问题日益突出,怎样降低其复发率是该领域研究的难点。该文对可能影响tPTX+AT术后复发的因素进行总结和讨论,为临床工作者进一步提高手术成功率,降低手术复发率,提高患者术后的生活质量,加强术后管理提供临床思路。Secondary hyperparathyroidism(SHPT)is one of the most common complications in uremia patients undergoing long-term hemodialysis treatment.SHPT patients after long-term dialysis treatment eventually developed into refractory SHPT.At this time,the effect of medical treatment is poor or even ineffective,and surgical treatment can make patients symptoms improve rapidly.At present,total parathyroidectomy+autologous transplantation(tPTX+AT)surgery is one of the main surgical methods for patients with refractory SHPT.However,in recent years,the rehabilitation management problem of patients with refractory SHPT after tPTX+AT surgery has become increasingly prominent,and how to reduce the recurrence rate is a difficult point in this field.This article summarizes and discusses the factors that may affect the recurrence after tPTX+AT surgery,so as to provide clinical ideas for clinicians to further improve the success rate of surgery,reduce the recurrence rate of surgery,improve the quality of life of patients after surgery,and strengthen the postoperative management.

关 键 词：继发性甲状旁腺功能亢进症 维持性血液透析 并发症 甲状旁腺全切除手术 自体移植术 手术治疗 复发 综述 

分 类 号：R581.1[医药卫生—内分泌]