富含血小板血浆在治疗薄型子宫内膜中的应用进展  

Progress in the application of platelet rich plasma in the treatment of thin endometrium

作　　者：张威(综述) 孟庆霞(审校)[1] ZHANG Wei;MENG Qingxia(Center of Reproduction and Genetics,the Affiliated Suzhou Hospital of Nanjing Medical University/Suzhou Municipal Hospital,Suzhou,Jiangsu 215002 China)

机构地区：[1]南京医科大学附属苏州医院/苏州市立医院生殖与遗传中心,江苏苏州215002

出　　处：《现代医药卫生》2024年第5期866-870,876,共6页Journal of Modern Medicine & Health

基　　金：江苏省苏州市卫健委临床重点病种诊疗技术专项项目(LCZX202109)。

摘　　要：在辅助生殖技术助孕过程中,不孕症患者常常因为子宫内膜过薄而导致周期取消,过薄的子宫内膜会导致胚胎反复种植失败,与较低的种植率、持续妊娠率和活产率相关。目前,临床上薄型子宫内膜的治疗效果不佳,如何改善薄型子宫内膜仍是一个尚未解决的临床难题。富含血小板血浆(PRP)作为一种潜在的新疗法,对子宫内膜发育不良或子宫内膜薄且对标准疗法无反应的患者具有积极作用。该文综述了PRP对薄型子宫内膜影响的最新研究进展,希望为辅助生殖领域中子宫内膜过薄的不孕症患者的临床治疗提供参考。In the process of assisted reproductive technology assisted pregnancy,infertile patients often have their cycles canceled due to a thin endometrium,which can lead to repeated embryo implantation failures,which are associated with lower implantation,ongoing pregnancy,and live birth rates.At present,the treatment of thin endometrium is currently ineffective and the improvement of thin endometrium remains an unresolved clinical challenge.Platelet-rich plasma(PRP)is a potential new therapy that could have a positive effect on patients with underdeveloped or thin endometrium and no response to standard therapy.This article reviews the latest research progress on the effects of PRP on thin endometrium with the hope of informing the clinical management of infertile patients with thin endometrium in the field of assisted reproduction.

关 键 词：富含血小板血浆 薄型子宫内膜 辅助生殖技术 不孕症 胚胎移植 妊娠结局 

分 类 号：R711[医药卫生—妇产科学]