黄芪黄酮类成分及其药理作用研究  

Research on Flavonoids of Huangqi(Astragali Radix)and Their Pharmacological Action

作　　者：何嘉郡 秦晨 贺廉清 王盼盼 曹惠妍 刘维丽[1] 刘秀波[2] 马伟[1] HE Jiajun;QIN Chen;HE Lianqing;WANG Panpan;CAO Huiyan;LIU Weili;LIU Xiubo;MA Wei(Heilongjiang University of Chinese Medicine,Harbin 150040,Heilongjiang,China;Heilongjiang University of Chinese Medicine,College of Jiamusi,Jiamusi 150040,Heilongjiang,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学佳木斯学院,黑龙江佳木斯150040

出　　处：《辽宁中医药大学学报》2024年第1期112-119,共8页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(821713927);中央支持地方高校改革发展资金人才培养高水平项目(ZYRCB2021008);黑龙江省中医药经典普及化研究专项课题(ZYW2022-071)。

摘　　要：黄芪是豆科黄芪属多年生草本植物。中药黄芪历史悠久,作为中国传统中药之一,具有应用范围广、药用价值高等特点。黄芪的化学成分主要包含黄芪甲苷、黄芪多糖、黄芪黄酮、氨基酸等。近年来药理研究表明黄芪中黄酮类成分具有抗肿瘤、抗炎、抗氧化、抗病毒、免疫调节、降血糖等多种药理作用,其抗肿瘤作用效果显著,成为近年来学者们广泛研究的热点。文章对黄芪黄酮的化学成分及其药理作用相关文献进行搜集、检索、查阅、归纳与整理,并进行系统概括与总结,以期为黄芪黄酮类成分进一步开发与利用提供理论依据。Huangqi(Astragali Radix)is a perennial herbaceous plant in the legume family Astragalus membranaceus.As one of the traditional Chinese medicines in China,Huangqi(Astragali Radix)has a long history and has the characteristics of wide application range and high medicinal value.The chemical composition of Huangqi(Astragali Radix)mainly includes astragalus IV,astragalus polysaccharides,astragalus flavonoids,amino acids,etc.In recent years,pharmacological studies have shown that the flavonoids in Huangqi(Astragali Radix)have anti-tumor,anti-inflammatory,antioxidant,antiviral,immunomodulatory,hypoglycemic and other pharmacological effects,and their anti-tumor effects are remarkable,which has become a hot spot for extensive research by scholars in recent years.In this paper,the chemical composition and pharmacological effects of astragalus flavonoids are collected,retrieved,reviewed,summarized and organized,and systematically summarized and summarized,in order to provide a theoretical basis for the further development and utilization of astragalus flavonoids.

关 键 词：黄芪 黄酮 化学成分 药理作用 

分 类 号：R285[医药卫生—中药学]