Medicinal Effects, Phytochemistry,Pharmacology of Euphorbia prostrata and Promising MolecularMechanisms  

作　　者：Nirmala Kumari Yadav Rakesh Yadav 

机构地区：[1]Department of Pharmacy,Banasthali Vidyapith,Banasthali(304022),Rajasthan,India [2]Department of Pharmaceutical Sciences,Indira Gandhi University,Meerpur,Rewari(122502),Haryana,India [3]National Forensic Sciences University,Tripura Campus,Agartala(799001),Tripura,India

出　　处：《Chinese Journal of Integrative Medicine》2024年第2期181-192,共12页中国结合医学杂志（英文版）

摘　　要：Euphorbiaceae is a large family of dicotyledonous angiosperms with diverse genera including Euphorbia prostrata(E.prostrata).Current research has provided scientific evidence for traditional uses of E.prostrata against diverse pathological conditions such as anti-hemorrhoidal,anti-inflammatory,analgesic,wound healing,antioxidant,antibacterial,leishmanicidal,antitumor activity,and so on.The phytochemical screening has revealed the presence of glycosides,phytosterols,flavonoids,polyphenols,tannins,and anthraquinones with chemical structures elucidation of their respective compounds.The uniqueness of such multifactorial compounds present in this species endorses it as the potent therapeutic or prophylactic choice for several fatal diseases.Although ethnomedical applications served as a significant citation for pharmacology,the molecular mechanism has not been reviewed yet.The present paper provides a comprehensive review of research outcomes,pharmacology,toxicology,and molecular signaling of phytochemicals of E.prostrata species as a reference for relevant researchers.The study of bioactive compounds in crude extracts and fractions,the demonstration of primary mechanisms of pharmacology,along with the addition of toxicity,and clinical trials,should be conceded in depth.This review underlines the E.prostrata species that can be a promising phytomedicine since we are committed to excavating more intensely into their pharmacological role.

关 键 词：Euphorbia prostrata EUPHORBIACEAE PHYTOCHEMICALS ethnomedical applications TOXICOLOGY molecularmechanism 

分 类 号：R285[医药卫生—中药学]