术前血管内超声钙化特征对非ST段抬高型急性冠脉综合征患者PCI术后冠脉再狭窄的预测价值  

Predictive value of preoperative intravascular ultrasound calcification characteristics for coronary in-stent restenosis in patients with non-ST-segment elevation acute coronary syndrome after PCI

作　　者：杜媚君 傅莉妃 DU Meijun;FU Lifei(Department of Special Inspection,YongKang Hospital of Traditional Chinese Medicine,YongKang 321300,China)

机构地区：[1]永康市中医院特检科,浙江永康321300

出　　处：《全科医学临床与教育》2024年第2期133-136,共4页Clinical Education of General Practice

摘　　要：目的 构建术前血管内超声钙化特征对非ST段抬高型急性冠脉综合征(NSTE-ACS)患者经皮冠状动脉介入(PCI)术后冠脉支架内再狭窄(ISR)的预测模型并探讨其预测价值。方法 回顾性选取行PCI术治疗的NSTEACS患者146例为研究对象,根据患者治疗预后是否发生冠脉ISR分为正常组89例和再狭窄组57例。收集患者术前血管内超声钙化特征等临床资料,并行单因素分析确定收集信息中的影响PCI术后冠脉ISR相关因素。对相关因素行二元logistic回归分析以筛选独立危险因素,并以独立危险因素建立预测模型,并采用受试者工作特征(ROC)曲线评估预测价值。结果 冠脉内钙化弧度大、钙化长度长、浅表型钙化类型等血管内超声钙化特征均是影响PCI术后冠脉ISR的危险因素(OR分别=1.44、1.03、2.93,P均<0.05),以此构建预测模型的ROC曲线线下面积(AUC)为0.88。结论 冠脉内钙化弧度大、钙化长度长、浅表型钙化等术前血管内超声钙化特征均为PCI术后冠脉ISR的危险因素,以此构建预测模型对PCI术后冠脉ISR的发生与否具有较高预测价值。Objective To establish a prediction model of preoperative intravascular ultrasound calcification characteris-tics for coronary in-stent restenosis(ISR)in patients with non-ST-segment elevation acute coronary syndrome(NSTE-ACS)after PCI and explore its predictive value.Methods One hundred and forty-six patients with NSTE-ACS who un-derwent percutaneous coronary intervention(PCI)were retrospectively selected as the study objects and divided into nor-mal group(89 cases)and restenosis group(57 cases)according to the prognosis of coronary ISR.Preoperative intravas-cular ultrasound calcification characteristics and other clinical data of patients were collected,and univariate analysis was conducted to determine the relevant factors affecting coronary ISR after PCI.The independent risk factors were screened by binary logistic regression analysis,and the prediction model was established based on the independent risk factors.Re-ceiver operating characteristic(ROC)curve was drawn and predictive value was evaluated.Results The characteristics of intravascular ultrasound calcification such as large arc of coronary calcification,long length of calcification and superfi-cial calcification type were independent risk factors affecting coronary ISR after PCI(OR=1.44,1.03,2.93,P<0.05),and the area under the ROC curve(AUC)established by the three indexes was 0.88.Conclusion The characteristics of preoperative intravascular ultrasound calcification,such as large arc of intracoronary calcification,long length of calcifi-cation and superficial calcification are independent risk factors for coronary ISR after PCI.Therefore,the construction of a prediction model has high predictive value for the occurrence of coronary ISR after PCI.

关 键 词：非ST段抬高型急性冠脉综合征 血管内超声 再狭窄 钙化特征 预测模型 

分 类 号：R541.4[医药卫生—心血管疾病]