生物波联合早期综合康复治疗对重型颅脑损伤昏迷患者促醒效果研究  

Study on the effect of biowave combined with early comprehensive rehabilitation on coma patients with severe craniocerebral injury

作　　者：陈冬艳 齐金芳 代琰 王利勇 王帅 董攀 李倩 宋宏颖 满慧静 CHEN Dong-yan;QI Jin-fang;DAI Yan;WANG Li-yong;WANG Shuai;DONG Pan;LI Qian;SONG Hong-ying;MAN Hui-jing(Depart-ment of High Pressure Oxygen,Cangzhou People′s Hospital,Cangzhou 061000,China)

机构地区：[1]沧州市人民医院高压氧科,河北沧州061000 [2]沧州市人民医院康复治疗科,河北沧州061000 [3]沧州市人民医院神经外科,河北沧州061000 [4]邢台市医专第一附属医院神经内科,河北邢台054000

出　　处：《创伤与急危重病医学》2023年第6期386-389,共4页Trauma and Critical Care Medicine

基　　金：河北省卫健委重点研发指导项目(20200281)。

摘　　要：目的 探讨生物波联合早期综合康复治疗对重型颅脑损伤昏迷患者促醒的效果。方法 选取自2019年2月至2022年12月收治的90例早期重型颅脑损伤昏迷患者为研究对象,采用随机数字表法分为常规组(早期综合康复治疗,n=45)与联合组(生物波联合早期综合康复治疗,n=45),比较两组治疗后格拉斯哥昏迷评分(GCS)、日常生活活动能力评分(ADL)、清醒率、瞳孔对光反射恢复情况、治疗后患者睁眼时间及并发症发生率等。结果 治疗后,两组GCS、ADL评分均高于治疗前,且联合组高于常规组,差异有统计学意义(P<0.05)。两组患者治疗后30、40 d的清醒率高于治疗后20 d,联合组在治疗后40 d后清醒率高于常规组,差异有统计学意义(P<0.05)。两组患者治疗后6、9 d的瞳孔对光反射恢复率高于治疗后3 d,且联合组治疗后3、6 d的瞳孔对光反射恢复率高于常规组,联合组瞳孔对光反射时间及睁眼时间低于常规组,差异均有统计学意义(P<0.05)。治疗后,两组患者并发症发生率比较,差异无统计学差异(P>0.05)。结论 生物波联合早期综合康复治疗在重型颅脑损伤昏迷患者促醒效果较好,能够有效减少患者昏迷时间,改善患者意识障碍。Objective To explore the effect of biowaves with early comprehensive rehabilitation therapy on awakening in coma patients with severe head injury.Methods A total of 90 coma patients with early severe craniocerebral injury admitted from February 2019 to December 2022 were selected as the study objects,and were divided into the combination group(biological wave combined with early comprehensive rehabilitation therapy,n=45)and the conventional group(early comprehensive rehabilitation therapy,n=45)by ran⁃dom number table method.After the treatment,Glasgow coma score(GCS),activity of daily living score(ADL),wake rate,pupil light reflex recovery,eye opening time and complications were compared between the two groups.Results After the treatment,GCS and ADL scores in the two groups were higher than before the treatment,and the combined group was higher than the conventional group,the difference was statistically significant(P<0.05).The wakefulness rate at 30 and 40 days after treatment was higher than 20 days after treatment in the two groups,and the wakefulness rate at 40 days after treatment in the combined group was higher than that in the conventional group,the difference was statistically significant(P<0.05).The recovery rate of pupil light reflex on 6 and 9 days after treatment was higher than that on 3 days after treatment in the two groups,and the recovery rate of pupil light reflex on 3 and 6 days af⁃ter treatment in combination group was higher than that in conventional group,and the pupil light reflex time and eye opening time in combination group were lower than that in conventional group,with statistical significance(P<0.05).After treatment,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Biowaves with early compre⁃hensive rehabilitation therapy with has a better effect on promoting consciousness among the patients with severe head injury and co⁃ma,which can effectively reduce the duration of coma and improve consciousness disorders.

关 键 词：生物波 颅脑损伤 昏迷促醒 神经康复 唤醒干预 

分 类 号：R651.15[医药卫生—外科学]