猪细小病毒病研究进展  

Progress on Porcine Parvovirus

作　　者：刘运超[1] 陈玉梅[1] 杨苏珍[1] 魏蔷[1] 郝慧芳[1] 柴书军[1] LIU Yun-chao;CHEN Yun-mei;YANG Su-zhen;WEI Qiang;HAO Hui-fang;CHAI Shu-jun(Henan Provincial Key Laboratory of Animal Immunology,Henan Academy of Agricultural Sciences,Zhengzhou,Henan,450002,China)

机构地区：[1]河南省农业科学院动物免疫学重点实验室,河南郑州450002

出　　处：《动物医学进展》2024年第3期107-110,共4页Progress In Veterinary Medicine

基　　金：“十三五”国家重点研发计划项目(2017YFD0501103);河南省农业科学院自主创新项目(2023ZC085,2023ZC087)。

摘　　要：猪细小病毒(Porcine parvovirus,PPV)是一种无囊膜DNA病毒,主要引起母猪繁殖障碍。该病毒在全世界广泛流行,我国猪场PPV感染率高达90%以上,给养猪业带来巨大经济损失。PPV经口、鼻传播,主要侵染猪的生殖器官,引起母猪的死胎、木乃伊胎和公猪的精液质量下降。临床采用接种疫苗的方式进行防控,起到了一定的效果。论文对病毒的基因组和蛋白特征、流行病学和疫苗研究进行综述,以期为PPV的基础研究和疫苗开发提供参考。Porcine parvovirus(PPV)is a non-envelope DNA virus,which mainly causes reproductive disorders in sows.The virus is widely prevalent in the world.The infection rate of PPV in China has reached more than 90%,which has brought huge losses to the pig industry.PPV mainly infects the reproductive organs of pigs,through the mouth and nose and causing the dead fetus of sows,mummified fetus and semen quality of boars to decline.Vaccination is generally used for prevention and control in clinic.In this paper,the development of genome,protein,virus epidemiology and vaccine were reviewed in order to provide reference for the basic research and vaccine development of PPV.

关 键 词：猪细小病毒 VLP组装 病毒抗原表位 VP2蛋白 

分 类 号：S852.65[农业科学—基础兽医学]